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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79602 | MTP | Autophagy | |
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of ora... | |||
T35689 | MTP 131 acetate | Others | |
MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging... | |||
T8831 | Elamipretide 2TFA | MTP-131 2TFA,RX-31 2TFA,SS-31,MTP-131,SS-31 2TFA,Bendavia | Others |
Elamipretide 2TFA (RX-31 2TFA) is a novel mitochondrion-targeted antioxidant. | |||
TP1095 | Elamipretide | MTP-131,RX-31,SS-31 | Others |
Elamipretide (MTP-131) is a mitochondria-targeted antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that reduces toxic reactive oxygen species (ROS) production and stabilizes cardiolipin, with blood-brain-barrier ... | |||
T12037 | Mifamurtide | L-MTP-PE,MTP-PE,CGP 19835 | Others |
Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects. | |||
TP2332 | Mifamurtide sodium hydrate | L-MTP-PE,Mifamurtide,Muramyl tripeptide | |
Mifamurtide protects mice against herpes simplex virus type 2. It also is a macrophage activator. | |||
TP1096 | Elamipretide TFA | SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA) | Others |
Elamipretide TFA (RX-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide[1]. | |||
TP1095L | Elamipretide acetate | MTP 131 acetate,Elamipretide acetate (736992-21-5 Free base) | |
Elamipretide acetate (MTP 131 acetate) is a derivative of Elamipretide, a small mitochondria-targeting tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that can be used in studies to reduce the production of toxic reactive o... | |||
TP2332L | Mifamurtide sodium | Muramyl tripeptide,CGP 19835A,L-MTP-PE,Mepact,Junovan | |
Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009. | |||
T27719 | KD-026 | SLx 4090,SLx4090,KD026,SLx-4090 | CETP |
KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies. | |||
T13784 | MTPPA | M 5011 | Others |
MTPPA (M 5011) is treating inflammation and pain. | |||
T27601 | IMTPPE | SID-3712502,SID 3712502,SID3712502 | |
IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression. | |||
T23033 | MTPG | Others | |
Group II/group III metabotropic glutamate receptor antagonist | |||
T6267 | Lomitapide | AEGR-733,BMS-201038 | CETP |
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring... | |||
T31992 | Granotapide | CETP | |
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an... | |||
T30506 | BMS-212122 | UNII-0Z473OO6GB,BMS212122,BMS 212122 | CETP |
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-deriv... | |||
T15006 | Dirlotapide | CP742033,Slentrol | Others , CETP |
Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by ... | |||
T2545 | Lomitapide Mesylate | BMS-201038 mesylate,AEGR-733 mesylate | CETP |
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein. | |||
T39303 | CP-346086 | ||
CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces pl... | |||
T16158 | PF-02575799 | Adenosine Receptor | |
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM). |