kinesin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3118	Dimethylenastron		Kinesin
	Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.		Kinesin
T4048	Monastrol	(±)-Monastrol	Apoptosis , Kinesin
	Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.		Apoptosis , Kinesin
T2039	GSK-923295		Apoptosis , Kinesin
	GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).		Apoptosis , Kinesin
T6209	CW-069	CW069	Kinesin , Microtubule Associated
	CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.		Kinesin , Microtubule Associated
T36816	S-trityl-L-Cysteine	STLC	Kinesin
	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...		Kinesin
T12359	Paprotrain	(alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile	Kinesin
	Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.		Kinesin
T6393	ARQ 621		Kinesin
	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.		Kinesin
T3120	K858 (Racemic)	K858 Racemic,K858	Apoptosis , Kinesin
	K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.		Apoptosis , Kinesin
T2255	SB-743921 hydrochloride	SB743921 HCl,SB743921	Kinesin , KSP
	SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).		Kinesin , KSP
T2103	Ispinesib	CK0238273,SB-715992	Apoptosis , Kinesin , KSP
	Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.		Apoptosis , Kinesin , KSP
T8342	BRD9876		Others , Kinesin , Microtubule Associated
	BRD9876 is a selective inhibitor of MM1S growth.		Others , Kinesin , Microtubule Associated
T9207	GW406108X	GW108X	Kinesin , Autophagy
	GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block autophagic flux.		Kinesin , Autophagy
T39994	Sovilnesib		Microtubule Associated
	Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.		Microtubule Associated
T9207L	GW406108X(Z/E)		Kinesin , Autophagy
	GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .		Kinesin , Autophagy
T23543	YIL 781		GHSR
	YIL 781 is a selective ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM), showing a weak affinity for kinesin receptors (K = 6 μM). YIL 781 improves glucose homeostasis in vivo and in vitro by blocking ghrelin secretion...		GHSR
TQ0318	Filanesib	ARRY-520,ARRY 520	KSP
	Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.		KSP
TQ0318L	ARRY 520 hydrochloride		KSP
	ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity.		KSP
T60026	KIF18A-IN-2		Microtubule Associated
	KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.		Microtubule Associated
T77586	Eg5-IN-1		Kinesin
	Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.		Kinesin
T9682	AZD-4877	AZD4877	Apoptosis , Kinesin
	AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and med...		Apoptosis , Kinesin