Search Result

Search Results for " collagenase "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T23906	Collagenase inhibitor CI-2	SC 40827
	SC 40827 is a Collagenase inhibitor CI-2.
T25393	Etarotene	RO15-1570,Arotinoid ethyl sulphone,RO-15-1570,RO 15-1570	Tyrosinase
	Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and can be used to study psoriasis.		Tyrosinase
TP1501L	CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)		MMP
	CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, an...		MMP
T29150	WAY-151693	WAY151693,WAY 151693
	WAY-151693 is an inhibitor of human collagenase-3 (MMP-13).
T78117	FN-439 TFA		MMP
	FN-439 TFA is a selective inhibitor of collagenase-1, exhibiting inhibition with an IC50 of 1 μM, and is utilized in cancer and inflammation research [1] [2].		MMP
T70972	RP 59794
	RP 59794 is a collagenase inhibitor.
TP2347	Peptide 78	Peptide78,Thr-met-arg-lys-pro-arg-ser-gly-asn-pro-asp-val-ala-asn,Peptide-78
	Peptide 78 is identical to peptide 74 except that serine replaces cysteine. It does not inhibit 72-kDa type IV collagenase.
T71546	SC-44463
	SC-44463 is an MMP inhibitor, also a collagenase inhibitor , and HDAC inhibitor.
T80719	Z-PDLDA-NHOH
	Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].
T24740	RS-104966
	RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.
T83722	FALGPA TFA	2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,2-Furanacryloyl-Leu-Gly-Pro-Ala-OH
	FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releas...
T69666	MMP-8 Inhibitor I
	MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
T41037	Ecamsule disodium
	Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of vario...
T82975	Aranciamycin
	Aranciamycin (Compound 1), an anthracycline antibiotic, exhibits collagenase inhibitory activity (IC50 3.7*10^-7 M) and can inhibit DNA synthesis in tumor cells [1].
TP1501	CTTHWGFTLC, CYCLIC
	This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic interven...
T71153	FN-439
	FN-439 is a selective inhibitor of collagenase-1, characterized by an IC50 value of 1 μM, indicating its effectiveness in inhibiting this enzyme. Due to its specificity and activity, FN-439 serves as a valuable tool for ...
T41079	MMP13-IN-2	MMP13-IN-2
	MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over...
T62846	Freselestat quarterhydrate
	Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent, orally active inhibitor of neutrophil elastase (Ki: 12.2 nM). quarterhydrate is more than 100-fold less active than other proteases such as trypsin, prote...

Compounds

Collagenase inhibitor CI-2

Synonym: RO15-1570,Arotinoid ethyl sulphone,RO-15-1570,RO 15-1570

Target: Tyrosinase

CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)

Synonym: WAY151693,WAY 151693

Synonym: Peptide78,Thr-met-arg-lys-pro-arg-ser-gly-asn-pro-asp-val-ala-asn,Peptide-78

Synonym: 2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine,2-Furanacryloyl-Leu-Gly-Pro-Ala-OH

Freselestat quarterhydrate

T62846

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T64812	Collagenase Type I	Collagenase I,Collagenase Type I (From microorganisms)	Others
	Collagenase Type I is a proteolytic enzyme that breaks down the peptide bonds in collagen, the main structural protein of connective tissue. Collagenase has been explored as a potential treatment option to break down her...		Others
T40080	(±)-Taxifolin	(±)-Dihydroquercetin	Antioxidant , Tyrosinase
	(±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin, a flavonoid commonly found in onion, silymarin, French maritime pine bark, and Douglas fir bark, with anti-tyrosinase and anti-fibrotic activity.Taxifoli...		Antioxidant , Tyrosinase
TN1153	Polyporenic acid C		Apoptosis , PARP , Caspase , PI3K
	Polyporenic acid C shows inhibitory activity against human collagenase.		Apoptosis , PARP , Caspase , PI3K
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone	3,3',4',5,6,7,8-heptamethoxyflavone	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone has neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging and photoprotective effects; it inhibits collagenase activity and induces type I pro...		Others
T1738	Taxifolin	(+)-Taxifolin,Dihydroquercetin,(+)-Dihydroquercetin	VEGFR , TNF , Tyrosinase , Adrenergic Receptor , Autophagy
	Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.		VEGFR , TNF , Tyrosinase , Adrenergic Receptor , Autophagy
T38497	(-)-Taxifolin	(-)-Dihydroquercetin
	(-)-Taxifolin is the less active enantiomer of Taxifolin, demonstrating vital anti-tyrosinase activity and notable inhibition against collagenase (IC50 = 193.3 μM). It is valued as an essential natural compound showing a...

Natural Products

Collagenase Type I

T64812

Synonym: Collagenase I,Collagenase Type I (From microorganisms)

Target: Others

(±)-Taxifolin

T40080

Synonym: (±)-Dihydroquercetin

Target: Antioxidant, Tyrosinase

Polyporenic acid C

TN1153

Synonym:

Target: Apoptosis, PARP, Caspase, PI3K

3,5,6,7,8,3',4'-Heptemthoxyflavone

TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone

Target: Others

Taxifolin

T1738

Synonym: (+)-Taxifolin,Dihydroquercetin,(+)-Dihydroquercetin

Target: VEGFR, TNF, Tyrosinase, Adrenergic Receptor, Autophagy

(-)-Taxifolin

T38497

Synonym: (-)-Dihydroquercetin

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02342	Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)	Hypoderma lineatum	E. coli
	This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-\|-Try-16 and 22-Arg-\|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P...
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o...
TMPH-00419	Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc)	C.perfringens	E. coli
	Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization. Has both...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPJ-00957	MMP-9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of s...
TMPH-00998	CD147 Protein, Human, Recombinant (aa 138-323, hFc)	Human	HEK293 Cells
	CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.
TMPJ-00362	MMP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo...
TMPH-02438	IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)	Rhesus	E. coli
	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammat...
TMPJ-01392	IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)	Cavia porcellus	E. coli
	Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and per...
TMPY-01229	SETD7 Protein, Human, Recombinant (His)	Human	E. coli
	Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine ...