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Natural Product Categories Natural Product Categories Caryophyllales
Caryophyllales is a large and diverse order of flowering plants that includes families such as Cactaceae, Amaranthaceae, and Polygonaceae, encompassing species adapted to extreme environments such as deserts and saline soils. Members of Caryophyllales produce a wide range of secondary metabolites, including betalains, alkaloids, saponins, and phenolic compounds. In biomedical research, Caryophyllales is important for its antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, with betalain pigments showing particular interest for oxidative stress modulation. Plants such as beetroot and quinoa also contribute nutritionally valuable phytochemicals. The order is a key model for studying environmental adaptation and the evolution of unique pigment systems in angiosperms.
- OrientinLutexin, Luteolin-8-glucosideT6S072128608-75-51. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.
- $48
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Cited - Zingibroside R1Ginsenoside Z-R1T496280930-74-1Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity.
- $48
SizeQTY - PlumbaginPlumbagone, Plumbagine, Plumbaein, 2-MethyljugloneT2841481-42-5Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Drosera and Nepenthes. It is also a component of the black walnut drupe.
- $34
SizeQTY Cited - Gallic acidGallate, 3,4,5-Trihydroxybenzoic acidT0877149-91-7Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
- $30
SizeQTY Cited - InosineNSC 20262, INO 495T043758-63-9Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Inosine has anti-inflammatory, immunomodulatory, antinociceptive and neuroprotective effects.
- $29
SizeQTY Cited - DesoxyrhaponticinDeoxyrhapontin, DeoxyrhaponticinTJS038730197-14-91. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney. 2. Desoxyrhaponticin and rhaponticin could be considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
- $40
SizeQTY - Emodin-1-O-β-D-glucopyranosideEmodin-1-O-glucosideT2S038938840-23-21. Emodin-1-O-β-D-glucopyranoside (Emodin-1-O-glucoside) has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin-1-O-β-D-glucopyranoside shows inhibitory effects on various tumor cells proliferation.
- $59
SizeQTY - EmodinFrangula emodinT2869518-82-1Emodin (Frangula emodin) is an 11β-HSD1 inhibitor with a selective IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice, respectively. Emodin has antiviral, anti-inflammatory, and anti-cancer effects. Emodin can improve metabolic disorders in diet-induced obese mice.
- $45
SizeQTY Cited - ResveratrolosideTN214438963-95-0Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.
- $73
SizeQTY - Betainetrimethylglycine, oxyneurine, lycine, glycine betaine, AbromineT3243107-43-7Betaine (trimethylglycine) is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.
- $29
SizeQTY Cited - Heterophyllin BT4S1796145459-19-4Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associated genes.
- $44
SizeQTY - RosavinRosavidinT388684954-92-7Rosavin (Rosavidin) has antidepressant and anxiolytic actions, helps balance all the neurotransmitters.
- $42
SizeQTY - PhyscionRheochrysidin, Physcione, Parietin, Emodin-3-methyl etherT3019521-61-9Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.
- $43
SizeQTY - Segetalin BTMA1644164991-89-3Segetalin B is a natural product from Vaccaria segetalis (Neck.) Garcke, has estrogen-like activity.
- $45
SizeQTY - Momordin IcMomordin 1cT341096990-18-0Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.
- $30
SizeQTY - RheinRhubarb yellow, Rheinic Acid, Rheic Acid, NSC 38629, MonorheinT2997478-43-3Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
- $31
SizeQTY Cited - BiliatresoneT304511801433-90-8Biliatresone, an environmental toxin isolated from the coccolithophores Dysphania glomulifera and D. littoralis, induced C57BL/6J neonatal cholangiopathy, induced a decrease in glutathione (GSH) levels, induced a significant decrease in SOX17 cholangiocyte levels, and induced extrahepatic cholangiocyte damage and fibrosis in mice.
- $199
SizeQTY - IsoorientinLuteolin-6-C-glucoside, HomoorientinT6S07224261-42-1Isoorientin (Homoorientin) has antioxidant activity.
- $32
SizeQTY Cited - CirsimaritinTQ01196601-62-3Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.
- $52
SizeQTY - RhapontinRhapontigenin glucoside, Rhaponticin, Rhaponiticin, PonticinT5S0384155-58-81. Rhapontin (Ponticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiabetic effect and could be potentially used as a new agent to treat type 2 diabetes mellitus and its complications.
- $35
SizeQTY - Chrysophanol 8-O-β-D-(6'-O-galloyl)glucopyranosideT82724266997-57-3Chrysophanol 8-O-β-D-(6'-O-galloyl)glucopyranoside is a naturally occurring anthraquinone glycoside that scavenges DPPH radicals and O2-.
- $189
SizeQTY - β-Apo-8'-carotenaltrans-β-apo-8'-carotenal, ApocarotenalT55821107-26-2β-Apo-8'-carotenal (Apocarotenal) is a carotenoid present in spinach and citrus fruits, utilized in fat-based foods (margarine, sauces, salad dressings), beverages, dairy products, and sweets.
- $45
SizeQTY - Fuegin(+)-FueginTN40836750-10-3Fuegin is a sesquiterpene compound isolated from the Polygonaceae plant Polygonum hydropiper.
- $1,508
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