T10254 |
AE-3763
|
291778-77-3
|
98%
|
|
AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).
|
T22451 |
UK-371804 HCl
|
256476-36-5
|
98%
|
|
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fol...
|
T15285 |
FK706
|
144055-55-0
|
98%
|
|
FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine ...
|
T17288 |
ZD8321
|
182073-77-4
|
98%
|
|
ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).
|
T13568 |
BCX 1470
|
217099-43-9
|
98%
|
|
BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.
|
TN4005 |
Erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether
|
613684-55-2
|
98%
|
|
erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether is a compound extracted from Brazilian rubber seed hulls and is an inhibitory activity against human le...
|
T13567 |
BCX 1470 methanesulfonate
|
217099-44-0
|
98%
|
|
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respecti...
|
T13412L |
ZM223 hydrochloride (2031177-48-5 free base)
|
|
98%
|
|
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
|
T8362 |
Benzamidine hydrochloride
|
1670-14-0
|
99.97%
|
|
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, r...
|
T8677 |
3,4 Dichloroisocoumarin
|
51050-59-0
|
99.9%
|
|
3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor
|
T0789 |
PMSF
|
329-98-6
|
99.9%
|
|
Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthe...
|
T2118 |
SC-514
|
354812-17-2
|
99.88%
|
|
SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
|
T3107 |
Alvelestat
|
848141-11-7
|
99.87%
|
|
Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.
|
T5S0689 |
Demethylwedelolactone
|
6468-55-9
|
99.8%
|
|
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on ...
|
T3423 |
ML281
|
1404437-62-2
|
99.77%
|
|
ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.
|
T20762 |
Sivelestat sodium tetrahydrate
|
201677-61-4
|
99.64%
|
|
Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. S...
|
T0372 |
Gabexate mesylate
|
56974-61-9
|
99.64%
|
|
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and...
|
T13389 |
ZD-0892
|
171964-73-1
|
99.53%
|
|
ZD-0892 is a selective and potent inhibitor of neutrophil elastase, inhibits human neutrophil elastase and porcine pancreatic elastase, reverses advanced pulmona...
|
T6986 |
Sivelestat
|
127373-66-4
|
99.52%
|
|
Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.
|
T8563 |
2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
|
1234707-32-4
|
99.49%
|
|
2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.
|