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(9)
By Target- Autophagy
- Apoptosis(3)
- Kinesin(1)
- Others(3)
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Results for "
unc-51 like kinase
" in TargetMol Product Catalog- Inhibitors & Agonists12
sbp-7455 
Cited
T88501884222-74-5
SBP-7455 potently inhibited ULK1 2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.
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Citedbl-918 
T83222101517-69-3
BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.
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SBI-0206965 Cited
SBI0206965
T21281884220-36-3
SBI-0206965 is a potent, selective, and cell-permeable autophagy kinase ULK1 inhibitor with an IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
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CitedULK-101 Cited
T54032443816-45-1
ULK-101 is a potent and selective inhibitor of ULK1 (IC50s: 8.3 30 nM for ULK1 ULK2). It can suppress autophagy.
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CitedLYN-1604 dihydrochloride
LYN-1604 2HCl(2216753-86-3 free base)
T8808L2310109-38-5
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
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(Rac)-BL-918
T126622435589-07-2
(Rac)-BL-918 is the racemate of BL-918, a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson's disease treatment [1].
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sr-17398
T288471496088-76-6
SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).
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MRT68921
T68991190379-70-4
MRT68921 is a potent and dual autophagy kinase ULK1 2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
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LYN-1604
LYN1604
T41232088939-99-3
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
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LYN-1604 hydrochloride
T396872216753-86-3
LYN-1604 hydrochloride, a powerful activator of UNC-51-like kinase 1 (ULK1) with an EC50 value of 18.94 nM, has significant implications in the study of triple-negative breast cancer (TNBC).
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GW406108X
GW108X
T92071644443-92-4
GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block autophagic flux.
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MRT68921 dihydrochloride
T91422080306-21-2
MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).
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