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(24)
By Target- STAT
- Apoptosis(7)
- JAK(4)
- Akt(2)
- Antibacterial(2)
- Antibiotic(2)
- DNA Methyltransferase(2)
- Ferroptosis(2)
- PROTACs(2)
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By Target By ResearchField- Cancer(1)
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Results for "
stat3/5
" in TargetMol Product Catalog.- Inhibitors & Agonists27
- Dye Reagents1
- PROTAC Products3
- Natural Products4
- Reference Standards3
- STAT3 ligand 5T203108STAT3ligand 5 is a STAT3 ligand, serving as a target protein ligand for the synthesis of the PROTAC degrader [SD-436].
- Inquiry Price
SizeQTY - SD-436SD436T2033952497585-50-7SD-436 is a selective and highly efficient STAT3 PROTAC degrader (DC50 = 0.5 μM), with an IC50 of 19 nM for STAT3, significantly higher than for STAT1/4/5/6. SD-436 depletes STAT3 and induces tumour regression in mouse leukaemia and lymphoma xenograft models.
- $263
SizeQTY - PROTAC ALK degrader-5T2171432379672-57-6PROTACALK degrader-5 (Compound 17) is a potent ALKPROTAC degrader with activities of 27.4 nM against EML4-ALK and 116.5 nM against NPM-ALK. It exhibits strong antiproliferative effects on H3122 and Karpas 299 cell lines and effectively inhibits the phosphorylation of ALK and STAT3. This compound is applicable for studying ALK-driven malignancies, such as human non-small cell lung cancer and anaplastic large cell lymphoma.
- Inquiry Price
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