pyrethroid

Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.

Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.

λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system.

D-Phenothrin ((-)-trans-Phenothrin) is a type II synthetic pyrethroid extensively employed in veterinary medicine for pest control on animals, crop protection, and the elimination of insects, mosquitoes, and human lice.

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its administration in rats has been observed to induce the development of hepatocellular tumors.

Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.

Tetramethrin is a type I pyrethroid insecticide that affects the inactivation process of sodium channels in insect neurons, leading to prolonged sodium currents.

Bifenthrin is a synthetic pyrethroid insecticide.Bifenthrin induces cell death in bovine mammary epithelial cells through ROS generation, disruption of calcium homeostasis, and alteration of the MAPK signaling cascade.Bifenthrin induces apoptosis by inducing cell-cycle arrest.

3-Phenoxybenzaldehyde cyanohydrin (2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile) is an intermediate of pyrethroid insecticides such as fenpermethrin.

Phenothrin (Sumithrin) is a synthetic pyrethroid used to kill adult fleas and ticks.

Bioresmethrin is a pesticide of synthetic pyrethroid.

(-)-trans-Permethrin ((-)-trans-NRDC-143) is a type of pyrethroid that effectively protects cattle against black flies.

Etofenprox is an orally active non-ester pyrethroid insecticide. It is toxic to various pests including Diptera, with mild effects on mammals and fish. This compound promotes liver tumor formation in rats and increases microsomal ROS levels. It is suitable for agricultural pest control and malaria-related research.

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.

Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.

Resmethrin, a synthetic pyrethroid insecticide, is used against a variety of insects.

Prallethrin is an airborne mosquito repellent and a non-fluorinated pyrethroid that targets lung surfactant proteins (SPs). It exhibits vapor toxicity and can bind to SPs through hydrogen bonding and hydrophobic interactions, impairing their function. Prallethrin is utilized in research concerning respiratory diseases, pathogenic infections, and malignant tumors.

Cyhalothrin is a synthetic pyrethroid insecticide that mimics the structure and insecticidal properties of natural pyrethrins.

Insecticidal agent 29 is a pyrethroid insecticide containing a pyridine heterocycle. It demonstrates insecticidal activity against Culex quinquefasciatus larvae, Aphis craccivora, and aphids. However, Insecticidal agent 29 shows no activity against Tetranychus cinnabarinus.

γ-Cyhalothrin is an orally active synthetic type II pyrethroid insecticide capable of penetrating the blood-brain barrier. It is the insecticidally active enantiomer of λ-Cyhalothrin. γ-Cyhalothrin disrupts voltage-gated sodium channels, causing reduced spontaneous activity and salivation in rats. It exhibits toxic effects on aquatic invertebrates and fish, affecting aquatic communities, and inhibits host-seeking behaviors of Ixodes scapularis nymphs in residential turfgrass areas. γ-Cyhalothrin is utilized in research related to insect control.

Profluthrin, a type of pyrethroid insecticide, is used as a mothproofing and insect repellent for clothing.

D-Tetramethrin is a type I synthetic pyrethroid insecticide (Insecticide) and a hepatotoxicity inducer. It triggers oxidative stress in the liver of zebrafish, induces apoptosis (Apoptosis), and inflammatory responses, leading to severe liver damage in zebrafish. D-Tetramethrin is applicable in studies related to hepatotoxicity.

Zeta-Cypermethrin is a type II pyrethroid insecticide that primarily targets voltage-gated sodium channels in nerve cells, causing delayed closure of these channels, which leads to continuous neural excitation and spasms. In fruit flies, Zeta-Cypermethrin can rapidly induce extremely high metabolic resistance through selection, and it shows in vitro genotoxicity on human peripheral blood lymphocytes.