pyrethroid

Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.

Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.

D-Phenothrin ((-)-trans-Phenothrin) is a type II synthetic pyrethroid extensively employed in veterinary medicine for pest control on animals, crop protection, and the elimination of insects, mosquitoes, and human lice.

Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its administration in rats has been observed to induce the development of hepatocellular tumors.

Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.

λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system.

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Bifenthrin is a synthetic pyrethroid insecticide.Bifenthrin induces cell death in bovine mammary epithelial cells through ROS generation, disruption of calcium homeostasis, and alteration of the MAPK signaling cascade.Bifenthrin induces apoptosis by inducing cell-cycle arrest.

3-Phenoxybenzaldehyde cyanohydrin (2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile) is an intermediate of pyrethroid insecticides such as fenpermethrin.

Phenothrin (Sumithrin) is a synthetic pyrethroid used to kill adult fleas and ticks.

Tetramethrin is a type I pyrethroid insecticide that affects the inactivation process of sodium channels in insect neurons, leading to prolonged sodium currents.

Bioresmethrin is a pesticide of synthetic pyrethroid.

(-)-trans-Permethrin ((-)-trans-NRDC-143) is a type of pyrethroid that effectively protects cattle against black flies.

Etofenprox, a synthetic pyrethroid, has insecticidal efficacy against mosquito larvae & on non-target organisms.

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.

Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.

Resmethrin, a synthetic pyrethroid insecticide, is used against a variety of insects.

Flumethrin is a pyrethroid insecticide. It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, and the treatment of parasitic mites in honeybee colonies.

Cismethrin is a pyrethroid insecticide.

Kadethrin is a synthetic pyrethroid. It was used as a pesticide.

kappa-Bifenthrin is a pyrethroid insecticide.

Acrinathrin is a pyrethroid used as an insecticide and an acaricide. Although resistance is developing, Acrinathrin is used to control the mite Varroa jacobsoni in beekeeping.

Fenvalerate (Evercide 2362) is a inhibitor of protein phosphatase 2B (calcineurin), a synthetic pyrethroid insecticide, and inhibits PP2B-Aα.High doses of Fenvalerate impair cognitive and behavioral development.Fenvalerate induces, through the Fas FasL signaling pathway, the induction of Fenvalerate induces germ cell apoptosis in mouse testis through the Fas FasL signaling pathway.

Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.