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Results for "

pro-apoptotic

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    94
    TargetMol | Inhibitors_Agonists
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α-Thujone
Thujone, ALPHA-(-)-THUJONE
T8193546-80-5
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
  • $37
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Tributyrin
NSC-661583, NSC661583, NSC 661583
T1967660-01-5
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
  • $50
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TargetMol | Inhibitor Sale
Lamellarin D
Lamellarine D
T3254597614-65-8In house
Lamellarin D (Lamellarine D), a hexacyclic pyrrolizidine alkaloid isolated from marine invertebrates, is a mitochondria-targeted topoisomerase I inhibitor and a pro-apoptotic agent.
  • $293
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(E)-Ferulic acid
trans-Ferulic acid, (E)-Coniferic acid
T5679537-98-4
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.t(E)-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • $34
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S-Adenosyl-L-methionine disulfate tosylate
Ademetionine disulfate tosylate
T675297540-22-2
S-Adenosyl-L-methionine disulfate tosylate is a methyl donor with oral activity. S-Adenosyl-L-methionine disulfate tosylate is a dietary supplement with effective antidepressant and pain-relieving effects. S-Adenosyl-L-methionine disulfate tosylate also has anti-proliferative, pro-apoptotic and anti-metastatic effects in cancer. S-Adenosyl-L-methionine can be used in the research of liver diseases and osteoarthritis.
  • $32
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2,5-Dihydroxyacetophenone
Quinacetophenone, DHAP, Acetylhydroquinone, 2-Acetylhydroquinone, 2-5-dihydroxyacetophenone
TCS2170490-78-8
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1 2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2,5-Dihydroxyacetophenone (Quinacetophenone) has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2,5-Dihydroxyacetophenone (Quinacetophenone) is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models.
  • $37
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Haemanthamine
T11534466-75-1
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsa
  • $1,520
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Resolvin D1
RvD1
T13864872993-05-0
Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macrophage phagocytosis of apoptotic cells.
  • $1,098
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Stearoylethanolamide
N-(2-Hydroxyethyl)octadecanamide
T13903111-57-9
Stearoylethanolamide(N-(2-Hydroxyethyl)octadecanamide) is a cannabinoid compound present in the brains of humans, rats, and mice with pro-apoptotic activity.
  • $40
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Timosaponin AIII
Timosaponin A3, Filiferin B, AneMarsaponin A3
T339541059-79-4
Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
  • $30
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Tetrac
Tetraiodothyroacetic acid, 3,3',5,5'-Tetraiodothyroacetic acid
T3671567-30-1
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac blocks the effects of T4 and 3,5,3'-triiodo-L-thyronine (T3) on the cell-surface thyroxine integrin αvβ3 receptors.Tetra has anti-angiogenic, anti-tumor activity and pro-apoptotic activity.
  • $39
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Irigenin
T3862548-76-5
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enhancing the expression of pro-apoptotic molecules in gastric cancer cells and has anti-cancer effects.
  • $40
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Haemanthamine hydrochloride
T73813
Haemanthamine hydrochloride, a crinine-type alkaloid derived from Amaryllidaceae plants, exhibits potent anticancer properties. It acts by targeting ribosomes, thereby inhibiting protein biosynthesis during the translation elongation stage. Additionally, this compound demonstrates pro-apoptotic, antioxidant, antiviral, antimalarial, and anticonvulsant activities [1] [2].
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Cantleyoside
TJS233432455-46-2
Cantleyoside, a natural cyclic enol ether terpene glycoside from Pterocephalus hookeri, has anti-inflammatory and pro-apoptotic effects, inhibiting inflammatory responses and promoting apoptosis in HFLS-RA cells through activation of the AMPK Sirt1 NF-κB signaling pathway.
  • $74
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Neochamaejasmine A
TMA091890411-13-5
Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately pro
  • $1,520
6-8 weeks
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Ergosterol peroxide
NSC31324, NSC 31324
TMA17432061-64-5
Ergosterol peroxide (NSC 31324) is a derivative from mushrooms with anti-tumor, pro-apoptotic anti-mycobacterial and anti-proliferative activities.Ergosterol peroxide has anti-inflammatory and antioxidant activities and is toxic to parasites.
  • $107
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Delphinidin 3-glucoside chloride
Delphinidin-3-O-glucoside chloride
TN15646906-38-3
Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) is a dietary phenolic substance found in Hibiscus sabdariffa extracts. Delphinidin 3-glucoside chloride has antioxidant activity, induces pro-apoptotic effects in B-cell chronic lymphocytic leukemia (B CLL), inhibits EGFR, and inhibits platelet aggregation. Delphinidin 3-glucoside chloride has antitumor activity, and is known to inhibit platelet aggregation by modulating pAKT IRF1 IRF1 IRF1 IRF1 IRF1 IRF1 IRF1 IRF1 IRF1. Delphinidin 3-glucoside chloride has anti-tumor activity and acts by regulating the pAKT IRF1 HOTAIR pathway.
  • $156
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