oxazolidinone

(S)-4-Benzyl-2-oxazolidinone, with CAS No. 90719-32-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (S)-4-Benzyl-2-oxazolidinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Amino-2-oxazolidinone (AOZ), the metabolite of Furazolidone, is routinely detected as an indicator of furazolidone residues in vivo.

Sutezolid (U-100480) is an oxazolidinone antimicrobial for the treatment of tuberculosis.

(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

AOZ-OVA is a hapten-carrier protein conjugate formed by coupling AOZ to chicken ovalbumin (OVA). As a hapten, AOZ alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

AOZ-BSA is a hapten-carrier protein conjugate formed by coupling AOZ to bovine serum albumin (BSA). As a hapten, AOZ alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.

(S)-4-Isopropyl-2-oxazolidinone ,with CAS No. 17016-83-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (S)-4-Isopropyl-2-oxazolidinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(R)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

(4R,5s)-(+)-4-methyl-5-phenyl-2-oxazolidinone ,with CAS No. 77943-39-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (4R,5s)-(+)-4-methyl-5-phenyl-2-oxazolidinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Amino-2-Oxazolidinone-D4 is a deuterated compound of 3-Amino-2-Oxazolidinone. 3-Amino-2-Oxazolidinone (T9344) has a CAS number of 80-65-9. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone. It is always be detected as a indicator of furazolidone residues in vivo.

3-Amino-2-oxazolidinone (Standard) is the standard substance of 3-Amino-2-oxazolidinone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone. It is always be detected as a indicator of furazolidone residues in vivo.

DuP 105 is an oral oxazolidinone, a novel synthetic antimicrobial compound effective against gram-positive bacteria.

PNU288034, a potent oxazolidinone antibiotic, demonstrates antimicrobial activity for the prevention and treatment of Gram-negative infections.

Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and streptococcus. The drug takes effect as the inhibitor of the initiation of bacterial protein synthesis.

Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.

Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory diseases of ENT organs and the respiratory tract (like sinusitis, tracheobronchitis, otitis, laryngitis, and rhinopharyngitis), and for maintenance therapy of asthma.

Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and a direct inhibitor of coagulation factor Xa with anticoagulant activity. Upon administration, it selectively binds to both free factor Xa and factor Xa within the prothrombinase complex, interfering with the conversion of prothrombin (factor II) to thrombin and preventing cross-linked fibrin clot formation. Rivaroxaban does not affect existing thrombin levels.

(S)-Tedizolid is the S-enantiomer of Tedizolid, a novel oxazolidinone with activity against Gram-positive pathogens.

Eperezolid (PNU-100592) is an oxazolidinone antibacterial agent. Eperezolid showed well in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml).

Radezolid (RX-1741) is a novel oxazolidinone antibiotic.

Tedizolid phosphate is a novel antibacterial prodrug. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. It also has effective activity a

Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).

DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.