npi

Anpirtoline hydrochloride (D-16949 hydrochloride) is a novel and potent 5-HT1B receptor agonist and 5-HT3 receptor antagonist with anti-injurious, analgesic, and antidepressant activity, and is used in the study of movement disorders.

Fenpicoxamid is a biochemcial.

NPI64 is a broad-spectrum coronavirus protease inhibitor which inhibits viral 3C and 3C-like protease.

Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium D3 bromide is a deuterium labeled Fenpiverinium bromide.

Quinpirole Hydrochloride (LY 171555), as an agonist with high affinity for dopamine receptor D2 D3, has been widely used to study the function of dopamine receptor D2 D3 in humans and mice

Enpiroline phosphate is an antimalarial compound.

FENPIPRAMIDE is an anticholinergic agent available as a hydrochloride salt. It serves as the active ingredient in certain veterinary compounds used as analgesics or detoxifying agents. Historically, FENPIPRAMIDE was employed as an antispasmodic in human obstetrics.

Enpiroline is an antimalarial compound.

Enpiperate is a blocker of Calcium channel.

Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.

Clenpirin is a bio-active chemical.

Difenpiramide is a non-steroidal anti-inflammatory agent with anti-inflammatory, analgesic, antipyretic, and diuretic activity.

Mudanpioside C is isolated from the peony plant.

Anpirtoline free base is a highly potent 5-HT1B receptor agonist. Anpirtoline has been shown to decreases central serotonin synthesis and attenuate aggressive behavior in vivo. Anpirtoline also acts as an antagonist at 5-HT3 receptors and can bypass the blood-brain barrier.

Quinpirole is a dopamine D2 D3 receptor agonist.

NPI52 (Compound E1) is an inhibitor of foot-and-mouth disease virus 3C protease (FMDV 3Cpro), with IC50 values of 0.05 µM in FRET assays and 0.11 µM in cell-based assays [1].

Mudanpioside H is a peony from the root bark of Paeonia lactiflora with a broad spectrum of antimicrobial activity and MIC values ranging from 100 to 500 microg mL.

Mudanpioside J is a natural product for research related to life sciences. The catalog number is TN5856 and the CAS number is 262350-52-7.

Genistein (NPI 031L) is a naturally occurring soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor, antioxidant, and anthelmintic properties, and also produces estrogen-like effects in the body.

Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.

Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM.[3]

Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule dynamics. This disrupts mitotic spindle assembly leading to cell cycle arrest at M phase and blockage of cell division.

MBRI-001 is a deuterium-substituted plinabulin derivative and a potent anti-cancer agent with better pharmacokinetic characteristics tand lower toxicity.

PD 144795 inhibited neutrophil adhesion to tumour necrosis factor-α (TNF-α)-activated human umbilical vein endothelial cells