42
7
27
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22371 | Mivacurium dichloride | Mivacurium chloride | AChR |
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg... | |||
T21550 | Blebbistatin | (±)-Blebbistatin | ATPase , Myosin |
Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell jun... | |||
T0112L | Diltiazem | Diltiazem free base,Dilticard,CRD-401,CRD401,Dilzen,CRD 401 | |
Diltiazem is a non-dihydropyridine (non-DHP) calcium channel blocker that relaxes the smooth muscle in arterial walls, thus opening (dilating) arteries, allowing easier blood flow, and lowering blood pressure, and is use... | |||
T24906L | Tuna AI acetate | Angiotensin-converting Enzyme (ACE) | |
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle. | |||
T12481 | Pipecuronium bromide | RGH-1106 | AChR |
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. | |||
T0156 | Rocuronium bromide | ORG 9426,ORG 9426 (Bromide) | AChR |
Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeleta... | |||
T0715 | Chlormezanone | Trancopal | Others , GABA Receptor |
Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. | |||
T0888 | Felbinac | Dapson,4-Biphenylacetic acid | COX |
Felbinac (Dapson), a topical medicine, is an active metabolite of fenbufen. It is belonging to the family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) of the arylpropionic acid class, which is use... | |||
T1594 | Vecuronium bromide | ORG NC 45 | AChR |
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. | |||
T3194 | Ro 46-2005 | Endothelin Receptor | |
Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM). | |||
T0939 | Phenytoin | Diphenylhydantoin,5,5-Diphenylhydantoin | Virus Protease , Sodium Channel |
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor... | |||
T2408 | Ostarine | MK-2866,GTX-024,Enobosarm | Androgen Receptor |
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostat... | |||
T71356 | Lanperisone HCl | ||
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43... | |||
T6038 | (-)-Blebbistatin | (S)-(-)-Blebbistatin | ATPase , Myosin |
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM. | |||
TP1115 | L-Asparaginase | L-ASNase | Others |
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a... | |||
T1158 | Phenoxybenzamine hydrochloride | NCI-c01661,NSC 37448,Phenoxybenzamine HCl | CaMK , Adrenergic Receptor |
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... | |||
T16344 | NS-2028 | Others , Guanylate cyclase | |
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028... | |||
T29846 | Alcuronium free base | Alcuronium,Alcuronum,Diallylnortoxiferine,Alcuronium kation,Alloferine | |
Alcuronium free base is a non-depolarizing skeletal muscle relaxant similar to Tubocurarine. It is used as an anesthesia adjuvant. | |||
T25636 | Laudexium | Laudexium ion,Laudexium cation | |
Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubatio... | |||
T68645 | Hexamethonium monotartrate | ||
Hexamethonium monotartrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle relaxant... | |||
T21449 | GYKI-52466 | GYKI 52,466,GYKI-5,2466,GYKI52,466 | |
GYKI-52466 is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >50 μM for AMPA-, kainate- and NMDA-induced responses, respectively) used as a Skeletal muscle relaxant, orally active ... | |||
T11522 | GYKI 52466 dihydrochloride | Others | |
GYKI 52466 dihydrochloride is orally active and non-competitive kainate- and AMPA-activated currents antagonist (IC50s: 7.5 μM and 11 μM). It is inactive against NMDA or γ-aminobutyric acid responses. It is a muscle rela... | |||
T28511 | Reglitazar | JTT-501,JTT501,PNU-182716,PNU182716,PNU-716 | |
Reglitazar is a PPARɑ agonist and PPARγ agonist. Reglitazar rapidly stimulates glucose disposal rates by enhancing insulin signal transduction in skeletal muscle. Reglitazar improves insulin resistance in genetic and non... | |||
T21427 | Mexiletine | Mexitil,Mexiletene,KO-1173,KO1173,KO 1173 | |
Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat musc... | |||
T33638 | Neostigmine Iodide | SB 24,SB24,TL1321,TL 1321,TL-1321,SB-24 | |
Neostigmine Iodide is a parasympathic compound used as a reversible acetylcholinesterase inhibitor to improve muscle tone in patients with myasthenia gravis and in routine anesthesia to reverse the effects of non-depolar... | |||
T69161 | Hexamethonium bromide dihydrate | ||
Hexamethonium bromide dihydrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle rel... | |||
T70269 | Hexamethonium chloride dihydrate | ||
Hexamethonium chloride dihydrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle re... | |||
T40431 | Anabaseine | ||
Anabaseine is a non-selective nicotinic agonist that stimulates all alpha-7 subtypes of AChRs, with a preference for skeletal muscle and brain. Additionally, it acts as a weak partial agonist at alpha-4 beta-2 nAChRs. | |||
T36335 | (S)-nitro-Blebbistatin | ||
(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in... | |||
T31845 | Forasartan | SC52458,SC 52458,SC-52458 | |
Forasartan is a non - peptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan and angiotensin II compete to bind AT1 receptor subtypes in vascular smooth muscle, thereby blocking angiotensin... | |||
T37702 | Pancuronium (bromide hydrate) | ||
Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a n... | |||
T36554 | TMB 8 (hydrochloride) | ||
TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671... | |||
T71207 | (R)-(+)-Blebbistatin O-Benzoate | ||
(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and revers... | |||
T12342 | P053 | Others | |
P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor with an IC50 of 0.5 μM. P053 is an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle and regulator of whole-body ad... | |||
TP2086 | AdTx1 | ||
Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenyl... | |||
T36400 | Para-amino-Blebbistatin | ||
para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of n... | |||
T37733 | AMP-PNP tetralithium | ||
Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules. Brady (1985) A novel brain ATPase with properties expect... | |||
T36384 | DL-Tyrosine-13C9,15N | L-Tyrosine-13C9,15N | |
L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylal... | |||
T76565 | PDC31 | ||
PDC31 (THG113.31; ILGHXDYK) is a D-amino acid-based oligopeptide that acts as an allosteric and non-competitive inhibitor of the FP Prostaglandin Receptor, used primarily as a smooth muscle contractile agent. It effectiv... | |||
T76305 | [Ala2] Endothelin-3, human | ||
[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3), characterized by the substitution of Ala for Cys residues. ET-3, a vasoactive peptide produced by human rhabdomyosarcoma cell lines but not expressed ... | |||
T36186 | Globotriaosylceramides (porcine) | ||
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceram... | |||
T35604 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | ||
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4934 | 1-Methyl-L-histidine | 3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine | Endogenous Metabolite |
1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | |||
T2520 | Desloratadine | Sch34117,NSC 675447 | Endogenous Metabolite , Histamine Receptor |
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot... | |||
T5279 | Ethylmalonic acid | alpha-Carboxybutyrate,2-Ethylmalonic acid | Others , Endogenous Metabolite |
Ethylmalonic acid (alpha-Carboxybutyrate) can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be as... | |||
T0962 | L-Hyoscyamine | Daturine,Hyoscyamine | AChR |
L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w... | |||
T4S1619 | L-Hyoscyamine sulfate | Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate | AChR |
L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits ... | |||
T3S0737 | Flavokawain A | Flavokavain A | Apoptosis , p38 MAPK |
NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant... | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03607 | Cofilin Protein, Human, Recombinant (His) | Human | E. coli |
CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments t... | |||
TMPY-05030 | PCDH7 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance... | |||
TMPJ-00071 | EPO/Erythropoietin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi... | |||
TMPH-02253 | TPM2 Protein, Human, Recombinant (His) | Human | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPH-03212 | TPM1 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | Baculovirus Insect Cells |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPY-03984 | TPM1 Protein, Human, Recombinant (His) | Human | E. coli |
TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth m... | |||
TMPH-02252 | TPM3 Protein, Human, Recombinant (GST) | Human | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPH-03213 | TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) | Rabbit | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPY-03600 | TPM4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-mu... | |||
TMPH-02205 | Titin Protein, Human, Recombinant (His) | Human | E. coli |
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the... | |||
TMPY-04471 | APEG1 Protein, Human, Recombinant (His) | Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr... | |||
TMPY-06762 | PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Baculovirus Insect Cells |
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance... | |||
TMPY-03863 | CAPG Protein, Human, Recombinant | Human | E. coli |
CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ ... | |||
TMPJ-01362 | UBAP1 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family membe... | |||
TMPH-01258 | DAG1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi... | |||
TMPJ-01386 | STUB1 Protein, Human, Recombinant | Human | E. coli |
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ... | |||
TMPY-03125 | SHP-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac... | |||
TMPJ-00158 | Apolipoprotein A-I/APOA1 Protein, Human, Recombinant | Human | E. coli |
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various... | |||
TMPY-01204 | SMYD2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SET and MYND domain-containing protein 2, also known as HSKM-B, SMYD2, and KMT3C, is a member of the SMYD protein family. It contains one MYND-type zinc finger and one SET domain. Not much is known about SMYD2. However, ... | |||
TMPY-02945 | Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG... | |||
TMPY-05353 | CCL26 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),... | |||
TMPY-02193 | GOLPH2/GOLM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colo... | |||
TMPJ-00948 | Endostatin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi... | |||
TMPY-02242 | Serpin B6 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-... | |||
TMPY-03504 | CBFB Protein, Human, Recombinant (His) | Human | E. coli |
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and os... | |||
TMPY-04461 | TRIB3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T... | |||
TMPH-03753 | MYLK Protein, Human, Recombinant (His) | Human | E. coli |
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos... |