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By Tag By Expression System- Baculovirus Insect Cells(2)
By Species- Human(2)
By SPR-compatible Buffer- Buffer exchange required(2)
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Results for "
mst 3
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Recombinant Protein2
- Antibody Products7
CompareSTK3, STE20, serine threonine kinase 24, RP11-111L24.5, MST3B, MST3, HEL-S-95
TMPY-04424
Expression system: Baculovirus Insect Cells
Length: 1-431, Partial
Activity: Enzyme activity
Length: 1-431, Partial
Activity: Enzyme activity
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CompareYSK3, TIIAC, serine threonine kinase 4, MST1, KRS2
TMPY-04398
Dysregulation of MST1 STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4 Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine threonine-protein kinase 4 (STK4) differentially regulates TLR3 4 9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker and therapeutic target for inflammation-induced HCC.
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