lta4h

Methyl arachidate (Methyl Icosanoate) is an esterified form of arachidic acid

DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor with an IC50 of 47 nM.

SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor.

ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase.

LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.

LTA4H-IN-5 (Compound H122) is an orally active inhibitor of leukotriene A4 hydrolase (LTA4H), effectively suppressing both its aminopeptidase and hydrolase activities with IC50 values of 0.38 nM and 16.93 nM, respectively. In C57 mice, it demonstrates favorable pharmacokinetic properties and shows efficacy in improving DNBS-induced ulcerative colitis in rat models.

LTA4H-IN-2 (compound (S)-2) acts as an orally active inhibitor targeting Leukotriene A4 Hydrolase, exhibiting potent activity with an IC 50 of less than 3 nM [1].

LYS006 is a highly efficient and selective LTA4H (leukotriene A4 hydrolase) inhibitor, which can be used for neutrophil-driven inflammatory diseases such as ulcerative colitis.

LTA4H-IN-3 (compound 9) functions as an inhibitor of LTA4H, demonstrating an IC50 of 28 nM [1].

4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.

DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.

JNJ-26993135 is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor.

LYS006 hydrochloride (1799681-85-8 Free base) is a potent LTA4H inhibitor of leukotriene A4 hydrolase. It can be used to study inflammatory and autoimmune diseases, including ulcerative colitis and NASH.

Methyl arachidate (Standard) is the standard substance of Methyl arachidate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Methyl arachidate (Methyl Icosanoate) is an esterified form of arachidic acid