Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • MAO
    (10)
  • Monoamine Oxidase
    (7)
  • Cholinesterase (ChE)
    (2)
  • Beta-Secretase
    (1)
  • COX
    (1)
  • Cytochromes P450
    (1)
  • NADPH
    (1)
  • Nrf2
    (1)
  • ROS
    (1)
  • Others
    (16)
Filter
Search Result
Results for "

hmao-b

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    36
    TargetMol | Inhibitors_Agonists
  • Natural Products
    2
    TargetMol | Natural_Products
hMAO-B-IN-5
T67879358343-63-2
hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be used in the study of Parkinson's disease. It is a promising compound in the treatment and diagnosis of central nervous system diseases.
  • $45
In Stock
Size
QTY
TargetMol | Inhibitor Sale
hMAO-B-IN-4
T677641666119-75-0
hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
  • $30
In Stock
Size
QTY
hMAO-B-IN-32
Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate
T7823228705-46-6
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
hMAO-B-IN-10
T201531
hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).
  • Inquiry Price
10-14 weeks
Size
QTY
Nrf2-ARE/hMAO-B/QR2 modulator 1
T603953035124-25-2
Nrf2-ARE hMAO-B QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 μM), selectively inhibited hMAO-B and QR2(quinone reductase-2,NQO2) (IC 50 = 8.05 and 0.57 μM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimer's disease model.
  • $36
In Stock
Size
QTY
hMAO-B/MB-COMT-IN-1
T60489
hMAO-B MB-COMT-IN-1 is a dual MAO-B MB-COMT inhibitor with IC50s of 2.5 μΜ for hMAO-B and 3.84 μΜ for MB-COMT. hMAO-B MB-COMT-IN-1 protects cells from oxidative damage and can be utilized in neurodegenerative disease research, such as Parkinson's Disease (PD) [1].
  • $1,520
10-14 weeks
Size
QTY
hMAO-B/MB-COMT-IN-2
T60658
hMAO-B MB-COMT-IN-2 is a dual inhibitor of MAO-B MB-COMT with IC50s of 4.27 μM and 2.69 μM for hMAO-B and MB-COMT, respectively. hMAO-B MB-COMT-IN-2 protects cells from oxidative damage and can be used in neurodegeneration disease research, such as Parkinson's Disease (PD) [1].
  • $1,520
10-14 weeks
Size
QTY
hmao-b-in-2
T606782454459-87-9
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective, BBB-penetrating, and competitively reversible inhibitor of hMAO-B (IC50 = 4 nM) used in Alzheimer's disease research. hMAO-B-IN-2 exhibits good neuroprotective effects and low toxicity in SH-SY5Y cells [1].
  • $1,520
6-8 weeks
Size
QTY
MAO-B-IN-17
T607122890188-81-3
MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) used in the study of central nervous system disorders, including Parkinson's.
  • $64
In Stock
Size
QTY
hMAO-B-IN-3
T610022581113-51-9
hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC50 = 47.4 nM) with favorable drug-like properties and a broad safety window, making it a suitable candidate for lead optimization and multitarget-directed ligand development [1].
  • $2,140
6-8 weeks
Size
QTY
hMAO-B-IN-6
T865852764830-43-3
Compound 17d (hMAO-B-IN-6) is an effective and selective hMAO-B inhibitor, demonstrating an IC 50 of 67.02 nM. It significantly ameliorates cognitive deficits induced by Scopolamine in Alzheimer's disease (AD) mice [1].
  • $1,520
6-8 weeks
Size
QTY
hMAO-B-IN-7
T865862955577-14-5
Compound 11n (hMAO-B-IN-7) is a potent inhibitor of human monoamine oxidase-B (hMAO-B) that can cross the blood-brain barrier (BBB). It demonstrates an IC 50 value of 0.79±0.05 μM and is useful in research related to Alzheimer's disease (AD) and Parkinson's disease (PD) [1].
  • $1,520
6-8 weeks
Size
QTY
hMAO-B-IN-9
T89331
hMAO-B-IN-9 (Compound 25c) acts as a non-competitive inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.58 µM (hMAO-B). Additionally, it functions as a chelator, forming complexes with iron ions which suppress ferroptosis induced by erastin. This compound exhibits antioxidant activity through the downregulation of reactive oxygen species (ROS) levels. It has also been shown to improve cognitive functions in mice without significant toxicity at a dose of 30 mg kg. Computer predictions suggest that hMAO-B-IN-9 is permeable to the blood-brain barrier.
  • Inquiry Price
Size
QTY
eckol
T2402588798-74-7In house
Eckol inhibits ultraviolet B-induced cell damage by a decrease in oxidative stress in human keratinocytes.This compound is unstable in powder form and other related salt forms are recommended.
  • Inquiry Price
3-6 months
Size
QTY
harman hydrochloride
Harmane hydrochloride(486-84-0 Free base)
T3158L21655-84-5
Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • $36
In Stock
Size
QTY
TargetMol | Inhibitor Sale
AChE/BChE/MAO-B-IN-1
T608912416910-82-0
AChE BChE MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE, and MAO-B that crosses the blood-brain barrier, exhibiting inhibitory effects on hAChE, hBChE, and hMAO-B with IC50s of 7.31, 0.56, and 26.1 μM, respectively. [AChE BChE MAO-B-IN-1] had a neuroprotective effect and was not significantly cytotoxic.
  • $41
In Stock
Size
QTY
TargetMol | Inhibitor Sale
chbo4
T7757898991-32-3
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the Ki value was 0.010 ± 0.005 μM.CHBO4 reduces cellular damage by scavenging intracellular reactive oxygen species (ROS), and can be used to study Parkinson's disease (PD).
  • $30
In Stock
Size
QTY
TargetMol | Inhibitor Sale
AChE-IN-82
T205513
AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.
  • Inquiry Price
Size
QTY
8-CSC
8 CSC,CSC
T23587148589-13-3
8-CSC is a dual agent endowed with good hMAO-B inhibitory activity (Ki: 235 nM in baboon liver mitochondria) and A2A affinity (Ki: 36 nM in rat brain striatal membranes receptor).
  • $1,520
6-8 weeks
Size
QTY
sl-25.1188
SL25.1188
T28798185835-97-6
SL-25.1188 is a monoamine oxidase B (MAO-B) inhibitor. SL-25.1188 is characterized by reversible binding, high brain uptake, and very slow plasma metabolism in vivo.
  • $1,670
6-8 weeks
Size
QTY
szv558
SZV-558, SZV 558
T288941648929-13-8
SZV558 is a potent inhibitor of both human and rodent MAO-B. SZV558 is safe in high doses with no hERG and mutagenic activities and demonstrated neuroprotection in an in vivo chronic model of PD.
  • $1,520
6-8 weeks
Size
QTY
TB5
T3596948841-07-4
TB5 is a potent, selective, and reversible inhibitor of hMAO-B.
  • $41
In Stock
Size
QTY
mao-b-in-15
T605732032436-79-4
MAO-B-IN-15 is a selective MAO-B inhibitor (IC50 = 13.5 μM) that forms π-π interactions with the Tyr 326 residue, and it can be utilized in Parkinson's disease research[1].
  • $1,520
6-8 weeks
Size
QTY
mao-b-in-16
T606511021238-13-0
MAO-B-IN-16 is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.55 μM, suitable for research in central nervous system disorders such as Parkinson's disease [1].
  • $1,520
6-8 weeks
Size
QTY