hmao-a

Obtusin is a natural product.

Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.

Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activities.

Rubrofusarin triglucoside, a glycoside isolated from Cassia obtusifolia Linn seeds, demonstrates inhibitory activity against human monoamine oxidase A (hMAO-A), exhibiting an IC50 value of 85.5 μM[1].

Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside derived from the seeds of Cassia obtusifolia, specifically inhibits hMAO-A isozyme activity with an IC50 value of 96.15 μM.

Acacetin 7-O-(6-O-malonylglucoside) is a reversible inhibitor of hMAO-A and hMAO-B (IC₅₀ = 2.34 and 1.87 μM), respectively, and can be used in the study of neurodegenerative diseases.

Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the active ingredients in the naphthylpyrone reference extract (NRE).