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Results for "

hiv 1 inhibitor 3

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    43
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    2
    TargetMol | Compound_Libraries
  • Natural Products
    4
    TargetMol | Natural_Products
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    2
    TargetMol | Recombinant_Protein
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    2
    TargetMol | Isotope_Products
HIV-1 inhibitor-3
T115641612841-22-1
HIV-1 inhibitor-3 is an HIV infection inhibitor.
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8-10 weeks
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HIV-1 integrase inhibitor 3
T115671638504-56-9
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
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8-10 weeks
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Apricitabine
AVX754, SPD754
T14313160707-69-7In house
Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.
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6-8weeks
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PDDC inhibitor
T697572232878-43-0In house
PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is a selective and highly potent nSMase2 inhibitor.
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8-10 weeks
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Gamibetal
4-Amino-3-hydroxybutyric Acid, 3-Hydroxy-GABA
T0028924-49-2
Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues. Also used in the preparation of HIV-1 inhibitors derived from Betulinic Acid (B330250).
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TargetMol | Inhibitor Sale
Lamivudine
GR109714X, BCH-189
T0682134678-17-4
Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
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Dolutegravir intermediate-1
1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid, 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
T110741335210-23-5
Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
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Q-VD-OPH
Quinoline-Val-Asp-Difluorophenoxymethylketone
T02821135695-98-5
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
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Lenacapavir
GS-6207
T114652189684-44-2
Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.[3]
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6-8 weeks
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Tizoxanide
TIZ, Desacetyl-nitazoxanide
T2279173903-47-4
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
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TargetMol | Inhibitor Sale
3'-Azido-3'-deoxy-5-methylcytidine
T101331282040-14-5
3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase (EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus [XMRV, CC50 = 43.5 μM].
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8-10 weeks
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TargetMol | Inhibitor Sale
beta-L-D4A
2'3'-didehydro-2'3'-dideoxyadenosine
FL00977057-48-9
beta-L-D4A, a nucleoside HIV-1 reverse transcriptase inhibitor, exhibits biological activity by terminating DNA chain synthesis in the 5'-3' direction.
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6-8 weeks
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3-Deazaadenosine hydrochloride
T1011186583-19-9
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
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BRD-6929
T10603849234-64-6
BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50:  1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin (a PKC Agonist) against latent HIV
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Cytochalasin A
T1092814110-64-6
Cytochalasin A, a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, is an inhibitor of HIV-1 protease (IC50 = 3 μM). It inhibits actin polymerization, interferes with microtubule assembly by reacting with sulfhydryl groups, and serves as an antibiotic and bactericidal active agent.
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DDX3-IN-1
T109861919828-83-3
DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.
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7-10 days
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Rottlerin
NSC 94525, NSC 56346, Mallotoxin
T1679182-08-6
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.
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HIV-1 inhibitor-78
T203356
HIV-1inhibitor-78 (compound 15f) is a potent and broad-spectrum non-nucleoside reverse transcriptase inhibitor, with an EC50 value of 3 nM against wild-type HIV-1. It is useful for research on HIV infections.
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BMIM-TFSI
BMI-TFSI, BMIM-TFSI, 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide
T204101174899-83-3
BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.
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10-14 weeks
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NPD4456
T205678859668-98-7
NPD4456 (Compound 3) is a 3-phenylcoumarin Vpr inhibitor. It binds competitively to Vpr and inhibits HIV-1 virus infection.
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10-14 weeks
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KNI-1657
T24266
KNI-1657 is a potent and selective HIV-1 protease inhibitor (Anti-HIV-1 pNL4-3, EC50: 3 nM). KNI-1657 is a highly potent HIV-1 Protease Inhibitor against Lopinavir.
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3-6 months
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Ursonic Acid
CCRIS 7123, NSC4060, Prunol, 3-Ketoursolic acid, Malol, TOS-BB-0966
T33236246-46-4
Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
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Dideoxyadenosine
T59494097-22-7
2',3'-Dideoxyadenosine is an inhibitor of HIV replication, exhibiting antiretroviral activity and antiviral efficacy [1].
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7-10 days
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HIV-1 inhibitor-47
T60342137448-39-6
HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3].
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6-8 weeks
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