halogenated

P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.

Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.

Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required.

Chiniofon (Ferron), a halogenated 8-hydroxyquinoline, is used as an antiamebic drug. This type of anti-amebic drug exerts an anti-amebic effect by inhibiting intestinal commensal bacteria and affects amoebic dysentery, but has no effect on extra-intestinal amoebic parasites.

4'-Bromomethyl-2-cyanobiphenyl is a halogenated benzonitrile used in protein-binding studies of quinoxaline angiotensin II receptor antagonists.

Rafoxanide as a dual CDK4 6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.

Clioquinol (Iodochlorhydroxyquin) is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.

Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry. It allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.

Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.

Methylprednisolone Aceponate (SH 440), a non-halogenated corticosteroid, is a potent anti-inflammatory agent.

HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity

Ropidoxuridine (IPdR) is a novel, orally available halogenated thymidine analogue that holds promise as a sensitizer for human tumors.Ropidoxuridine is an orally available and bioavailable IUdR (5-iodo-2'-deoxyuridine) prodrug.

1,1-Dibromo-3-chloroacetone is a halogenated disinfection byproduct (DBP) formed under high bromide levels when chlorine or chloramine is used as a secondary disinfectant in ozone-chlorine and ozone-chloramine processes.

1,1,3-Tribromo-3-chloroacetone is a chemical compound that acts as a halogenated disinfection byproduct (DBP) formed in the presence of elevated bromide levels during chlorine or chloramine use as a secondary disinfectant, attributed to reactions between ozone-chlorine and ozone-chloramine.

12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV replication in CEM-SS T cells with an EC50 value of 38 µM.

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium-potent, non-halogenated double-ester of hydrocortisone, with a favorable benefit risk ratio for treating inflammatory skin disorders.

1,3-Dibromo-1,3-dichloroacetone is a chemical compound that forms as a disinfection byproduct (DBP) from the use of halogenated ozone-chlorine and ozone-chloramine, especially at elevated bromide concentrations, when used as secondary disinfectants.

PTERULONE is a novel halogenated antibiotic derived from the fermentation of Pterula sp. 82168. This compound features a 1-benzoxepin system and undergoes chlorination.

1,1,1,3-Tetrachloroacetone, a halogenated compound, is known to form ozone-chlorine and ozone-chloramine disinfection byproducts (DBPs) when elevated bromide levels are present in water treated with chlorine or chloramine as secondary disinfectants.

Compound 1059182-21-6 features a cyclic structure characterized by a nitrogen atom occupying an apex (corner) within the heterocycle. Its molecular scaffold integrates aromatic properties due to the presence of a conjugated system, while the inclusion of hydroxyl (-OH) groups confers reactive potential for subsequent modification. Additionally, a halogenated component, specifically a bromine atom, is attached to the aromatic ring, enhancing its propensity for undergoing further synthetic transformations.

4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.

RM-5038 is a halogenated thiazole compound with multiple pharmacological properties, capable of combating a broad range of parasites, bacteria, and viruses through at least three mechanisms of action. Specifically, in respiratory viruses, RM-5038 can inhibit the replication of Paramyxoviridae and Pneumoviridae at the post-translational level.

4-Bromo A23187, a halogenated analog of the calcium ionophore A-23187, acts as a calcium modulator and induces apoptosis in various cells.

3-Bromothiophene is a 3-halogenated thiophene substituted with a bromine atom, offering electrochemical stability, low porosity, and a high π-π* lowest transition energy. It is commonly utilized as a monomer in conductive polymers.