fgf21

Expression system: HEK293 Cells
Length: 29-209, Full Length of Mature Protein
Activity: ELISA、SPR

FGF-21 Protein, Human, Recombinant (CHO, His) is expressed in CHO Cells. The accession number is Q9NSA1.

FGF-21 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q9JJN1.

Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat low-carbohydrate diet. Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.

FGF-21 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q9NSA1.

Expression system: HEK293 Cells
Length: 29-209, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-210, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 30-983, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 53-994, Partial
Activity: SPR