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Search Results for " exonuclease "

8

Compounds

Cat No. Product Name Synonyms Targets
T6456 CRT0044876 NSC 69877,7-NO2-ICA,NSC 69877,7-Nitroindole-2-Carboxylic Acid DNA/RNA Synthesis
CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
T38709 PFM39
PFM39, a Mirin analog, is a potent and selective inhibitor of MRE11 exonuclease activity, specifically targeting the inhibition of phosphate rotation necessary for double-stranded DNA (dsDNA) exonuclease function. Import...
T3134 (Z)-Mirin Mirin ATM/ATR
(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
T9168 NSC 617145 NSC617145,NSC-617145 DNA/RNA Synthesis
NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
T74702 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits attributes akin to LNA, including hybridization and mismatch discrimination capabilities. Additionally, it demonstrates resistanc...
T76102 Carboxypeptidase B
Carboxypeptidase B, a peptide exonuclease, specifically degrades peptide chains by progressively hydrolyzing from the C-terminal, releasing free amino acids. It acts exclusively on peptide bonds with basic amino acids (s...
T78938 H3B-968 DNA/RNA Synthesis
H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease activities. While WRN is known for its synthetic lethal acti...
T60273 Mirin
Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC 50 =12 μM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activi...
TargetMol