choleretic

Anethole trithione (Anetholtrithion) is a bile secretion-stimulating drug that restores salivation and relieves the discomfort of dry mouth in chemotherapy-induced xerostomia.

Bendazac (Bendazolic acid) is an anticataract drug. It may act by preventing protein denaturation.

Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.

Cicloxilic acid(Cycloxilic acid) has choleretic activity and inhibits biliary cholesterol output.

Piprozolin (W 3699) is a new type of choleretic acid that shows slight analgesic properties at high doses during chronic experiments.Piprozolin has a slight induction of certain enzymes of the oxidative system.

Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).

Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. Chenodeoxycholic acid acts as a detergent to dissolve fat for intestinal absorption and is reabsorbed by the small intestine. Chenodeoxycholic acid is used as a choledocholithiasis, choledocholithiasis and laxative, as well as to prevent or dissolve gallstones.

Menbutone (Genabilin) is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.

4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.

Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM), EphA2 antagonists (IC50=48, 66 μM) and EphB4 antagonists (IC50=141 μM). Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.

Deoxycholic acid (DCA) is a natural product and a TGR5 receptor agonist with cell permeability and oral activity. As a metabolite of intestinal flora, this compound is widely used in research on bile acid signal transduction, glucose and lipid metabolism, and anti-inflammatory mechanisms, and has shown therapeutic potential in diabetes and liver disease models.

Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.

Azintamide is a choleretic. It has shown effective and safe for dyspepsia symptoms when Domperidone therapy is not satisfactory.

Cimepanol is a cyclohexane derivative that functions as a sedative, a choleretic agent, and a digestive regulator.

Fenocinol, a diarylmethane derivative, exhibits choleretic properties.

Clorindanic acid is an indanol derivative known for its choleretic activity.

VUN14950, [3-Pyridinecarboxylic acid, 1-(4-methylphenyl)ethyl ester], is a choleretic agent.

Terbuprol was developed as a choleretic agent.

Febuprol, a choleretic drug, stimulates bile secretion. In addition, it also has lipid-lowering (lowering blood lipid) and spasmolytic (anticonvulsant) properties.

Cytaphat is a compound with liver-protective properties. It exhibits antioxidant, membrane-stabilizing, and choleretic effects. Cytaphat can be applied in research involving acute toxic liver diseases and liver injury.

Florantyrone (Zanchol) is a choleretic agent that increases the volume of bile without affecting its bile acid content. Zanchol stimulates hepatic cholesterol synthesis, significantly raises plasma cholesterol levels, and increases liver weight, but does not significantly affect intestinal cholesterol synthesis. Florantyrone can be used in the study of biliary dyskinesia.

Cyclobutyrol is a choleretic agent. It also inhibits biliary lipid secretion.

Cantabiline sodium is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in analytical chemistry for the determination of NITRIC ACID.

Nafcaproic acid (DA-808) is a synthetic choleretic agent.