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(6)
By Target- BMI-1
- Apoptosis(3)
- Autophagy(2)
- DNA/RNA Synthesis(1)
- E1/E2/E3 Enzyme(1)
- ERK(1)
- Epigenetic Reader Domain(1)
- Estrogen Receptor/ERR(1)
- Others(3)
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Results for "
bmi-1
" in TargetMol Product Catalog- Inhibitors & Agonists13
- Dye Reagents1
- Natural Products1
- Recombinant Protein1
- Antibody Products2
XMD8-92 
T18431234480-50-2
XMD8-92 is an effective and specific BMK1 ERK5 inhibitor (Kd: 80 nM).
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BMI-1026
T89253477726-77-5
BMI-1026 is a cyclin-dependent kinase 1 (Cdk1) inhibitor with an IC50 of 2.3 nM. It induces cell apoptosis by blocking the G2-M phase transition.
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EBMI-13B
T2402421202-53-9
EBMI-13B is a potent and selective isozymes CA-VA and CA-VII activator.
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BMI-135
T2000981608099-90-6
BMI-135, a selective estrogen mimic, demonstrates agonist activity for the estrogen receptor and induces a rapid endoplasmic reticulum stress response (UPR) alongside apoptosis in breast cancer cells.
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PRT4165
Cited
NSC600157, PRT 4165
T311031083-55-3
PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.
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CitedPTC-209 Cited
PTC209, PTC 209
T2345315704-66-6
PTC-209 is a potent and selective BMI-1 inhibitor.
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CitedUnesbulin
PTC596
T125751610964-64-1
Unesbulin (PTC596) is an orally active, selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
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PTC-209 hydrobromide
PTC-209 HBr
T61781217022-63-3
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
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PTC-028
T166801782970-28-8
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
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1,6,7-Trihydroxyxanthone
TN250725577-04-2
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.
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BMIM-TFSI
BMI-TFSI, BMIM-TFSI, 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide
T204101174899-83-3
BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.
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QW24
T626172416312-06-4
QW24 down-regulates BMI-1, exhibits potent antitumour effects and is used as an effective therapeutic agent in the treatment of clinical colorectal cancer.
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SH498
T633742125724-38-9
SH498 is a novel Bmi-1-mediated anti-tumor agent with significant anti-proliferative effects.
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