adenosine monophosphate

Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor, an EC 3.1.3.1 (alkaline phosphatase) inhibitor and an adenosine A1 receptor agonist.

Adenosine monophosphate-D12 dilithium is a deuterium-labeled variant of adenosine monophosphate. This compound acts as an agonist of the adenosine A1 receptor and exhibits significant antiviral activity against HSV-1 and HSV-2. Additionally, adenosine monophosphate is a crucial cellular metabolite involved in energy homeostasis and signal transduction regulation.

Adenosine monophosphate-13C10,15N5 disodium isodium is Adenosine monophosphate disodium (T65979) labeled with 13C and 15N. It serves as an agonist for the adenosine A1 receptor and demonstrates significant antiviral activity against HSV-1 and HSV-2. Additionally, Adenosine monophosphate is a crucial cellular metabolite involved in the regulation of energy homeostasis and signal transduction.

Adenosine-2'-monophosphate (2'-AMP) is a nucleoside derived from the conversion of 2',3'-CAMP. It inhibits inflammatory cytokine production by microglia and suppresses TNF-α and CXCL10 production in activated primary mouse microglia through A2A receptors.

Adenosine 5'-monophosphate triethylammonium salt is a useful organic compound for research related to life sciences and the catalog number is TNU1647.

Adenosine monophosphate-13C10,15N5 is a labeled form of adenosine monophosphate (TMSM-0379) with 13C and 15N isotopes. It acts as an agonist of the adenosine A1 receptor. Additionally, adenosine monophosphate exhibits significant antiviral activity against HSV-1 and HSV-2 and is a crucial cellular metabolite involved in energy homeostasis and signal transduction.

Adenosine monophosphate-15N5,D12 dilithium is a deuterated and 15N-labeled form of Adenosine monophosphate. Acting as an agonist for the adenosine A1 receptor, it exhibits significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a crucial cellular metabolite involved in regulating energy homeostasis and signal transduction.

Adenosine monophosphate-13C10 dilithium is a 13C-labeled form of adenosine monophosphate. Serving as an agonist for the adenosine A1 receptor, adenosine monophosphate exhibits significant antiviral activity against HSV-1 and HSV-2. It plays a crucial role as a cellular metabolite in regulating energy homeostasis and signal transduction.

Adenosine monophosphate-15N5 dilithium is an isotopic derivative of adenosine monophosphate labeled with 15N. Adenosine monophosphate acts as an agonist for the adenosine A1 receptor (adenosine A1 receptor). It exhibits significant antiviral activity against HSV-1 and HSV-2 and is a crucial cellular metabolite in regulating energy homeostasis and signal transduction.

Adenosine monophosphate (Standard) is a reference standard of adenosine monophosphate, suitable for quantitative analysis, quality control, and biochemical studies. Adenosine monophosphate (AMP) is an important intracellular nucleotide metabolite that plays a central role in energy metabolism, particularly by regulating the AMP-activated protein kinase (AMPK) signaling pathway involved in cellular energy sensing and homeostasis.

2-Chloro-2′-deoxyadenosine monophosphate is an anticoronavirus agent. It exhibits significant inhibitory effects against wild-type novel coronaviruses, various novel coronavirus variants (Beta, Delta, Omicron), and other coronaviruses, such as human coronavirus 229E, human coronavirus OC43, human coronavirus NL63, and mouse coronavirus MHV.

Cyclic AMP (cAMP) (Adenosine 3',5'-cyclophosphate) combined with vitamin C treatment of children with viral myocarditis has exact curative effect, and it can improve cardiac function of patients and improve immune function.

cAMP sodium(Cyclic adenosine monophosphate sodium) is a derivative of adenosine triphosphate (ATP) and a cellular second messenger. It transmits signals within cells that are carried by primary messengers (such as adrenaline) unable to enter the cell, performing crucial regulatory functions.

Gizzerosine 2HCl, a substance produced during the heat treatment of fishmeal, induces histopathological lesions in broiler chicks and increases intracellular cyclic adenosine-3',5'-monophosphate levels in isolated chickens of origin.

Adenosine 5'-monophosphate monohydrate (5'-AMP) , also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. Adenosine 5'-monophosphate monohydrate consists of a phosphate group, the sugar ribose, and the nucleobase adenine. As a substituent it takes the form of the prefix adenylyl-.

Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.

Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Salbutamol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, Salbutamol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.

5'-Guanylic acid (5'-guanosine monophosphate) is implicated in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (APRT), and the 2-hydroxyglutric aciduria pathway.

Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.

2′-Deoxyadenosine 5′-monophosphate disodium (a nucleic acid AMP derivative) is a deoxyribonucleotide in DNA, used for studying adenosine-based interactions in DNA synthesis and damage analysis.

5'-Guanylic acid disodium salt (GMP-5) is a purine ribonucleoside monophosphate. L-Glutamic acid and guanosine monophosphate are biosynthesized from xanthylic acid and L-glutamine via GMP synthase [glutamine-hydrolyzing]. Guanosine triphosphate and guanosine monophosphate are biosynthesized from diguanosine tetraphosphate via bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin, telithromycin, tobramycin, and erythromycin action pathways, and several metabolic disorders including AICA-ribosiduria, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and 2-hydroxyglutric aciduria (D and L form) pathways. Guanosine monophosphate is also found in foods like onion-family vegetables, millet, Chinese water chestnut, and red rice, serving as a potential biomarker for the consumption of these foods.

Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5'-monophosphate disodium salt has been shown to have a variety of biochemical and physiological effects. It has been shown to increase cell metabolism, gene expression, and protein synthesis.

Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinyl-adenosine 5'-monophosphate (GARMT) with K_i values of 1.3 nM, 7.2 nM, and 65 nM respectively. This inhibits the formation of precursor purine and pyrimidine nucleotides and cancer cell proliferation, making it suitable for research into pleural mesothelioma and non-small cell lung cancer (NSCLC).