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Search Result

Search Results for " txa2 "

20

Compounds

Cat No. Product Name Synonyms Targets
T34862 Thromboxane A2 Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2
Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction.
T12268 NTP42 Prostaglandin Receptor , PPAR
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
T6236 Ozagrel OKY-046,Domenan Thrombin , Prostaglandin Receptor
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...
T6625 Ozagrel hydrochloride Ozagrel HCl,OKY-046 HCl Thrombin , Prostaglandin Receptor
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
T10783 CGS 15435 PPAR
CGS 15435 is a potent thromboxen (TxA2) synthetase inhibitor (IC50: 1 nM). CGS 15435 acts on PGI2 synthase, cyclooxygenase and liposynthase with much less selectivity than on thromboxin synthase.
T68022 Sulotroban PPAR
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
T25741 Linotroban HN 11500,CL-871502 PPAR
Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.
T27630 Isbogrel CV4151,CV-4151,CV 4151 Prostaglandin Receptor
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.
T11339L Furegrelate PPAR
FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.
T11825 LCB-2853 PPAR
LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.
T31213 Dazmegrel UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485 PPAR
Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.
T3915 Ginsenoside Ro Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V Calcium Channel , Reductase , Prostaglandin Receptor
Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.
T15577 Indobufen Ibustrin COX
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue fac...
T15049 Daltroban BM-13505,SKF 96148 PPAR
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
T11339 Furegrelate sodium U-63557A PPAR
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.
T68086 Imitrodast Thrombin
Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiovascular diseases, and can be used in studies of arterial th...
T0212 Seratrodast AA 2414,ABT-001 COX , Prostaglandin Receptor , PPAR
Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained ma...
T67959 Pirodomast Thrombin , Serine Protease
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas...
T17039 Terbogrel BIBV 308SE Prostaglandin Receptor
Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a...
T2396 Ramatroban BAY u3405 GPR , Prostaglandin Receptor , PPAR
Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma.
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