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Search Results for " sr1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T1831 StemRegenin 1 SR1 AhR , Aryl Hydrocarbon Receptor
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
T6082 SSR128129E SSR FGFR
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.
T23383 SR11237 SR 11237 Others , RAR/RXR 
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
T23389 SR1664 SR 1664 PPAR
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR...
T4407 SR17018 Opioid Receptor
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
T4594 SR1078 SR 1078 ROR
SR1078 is an agonist of retinoic acid receptor-related orphan receptor (ROR)α/γ.
T12998 SR10067 Others , Autophagy
SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbα/β(IC50 of 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively),has anxiolytic activity.
T28856 SSR180711 hydrochloride SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl AChR
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
T5163 SR1001 ROR
SR 1001 is an inverse agonist for RORα/RORγ (Kis: 172/111 nM).
T28855 SSR126768A SSR-126768A,SSR 126768A Oxytocin Receptor
SSR126768A is a novel and selective, orally active and potent oxytocin (OT) receptor antagonist with inhibitory effects on uterine contractions for the prevention of preterm labor.
T60037 SR15006 DNA/RNA Synthesis
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
T16928 SR144528 Cannabinoid Receptor
SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).
T6994 SR12813 SR-12813,SR 12813,GW 485801 HMG-CoA Reductase , Autophagy
SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.
T22429 SR18662 DNA/RNA Synthesis
SR18662, an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM, reduces the viability of multiple colorectal cancer cell lines and induces apoptosis.
T24828 SR14150 SR-14150,SR 14150
SR14150 is a partial agonist of high-affinity NOP receptor.
T28846 SR16835 AT-202,AT202,SR 16835,SR-16835
SR16835 is a NOP receptor agonist, with low-affinity bifunctional activity at the μ opioid receptor.
T12999 SR121566A Others
SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).
T62239 HSR1304
HSR1304 (Compound 5d) is a potent inhibitor of NFκB, a multifunctional transcription factor involved in a wide range of human diseases (e.g. cancer, chronic inflammation). HSR1304 has potential for research in cancer dis...
T26223 SR1555 HCl SR-1555,SR1555,SR 1555
SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been involved in the pathology of several autoimmune diseases such as rheumatoid arthriti...
T28845 SR142948A HCl SR142948A,SR 142948A,SR-142948A,SR142948A hydrochloride
SR 142948A is a non-peptide antagonist of neurotensin receptor. SR 142948A affects the expression of c-Fos and has properties of antipsychotic agent. SR 142948A blocks hypothermia and analgesia induced by neurotensin. It...
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