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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1831 | StemRegenin 1 | SR1 | AhR , Aryl Hydrocarbon Receptor |
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. | |||
T6082 | SSR128129E | SSR | FGFR |
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs. | |||
T23383 | SR11237 | SR 11237 | Others , RAR/RXR |
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. | |||
T23389 | SR1664 | SR 1664 | PPAR |
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR... | |||
T4407 | SR17018 | Opioid Receptor | |
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. | |||
T4594 | SR1078 | SR 1078 | ROR |
SR1078 is an agonist of retinoic acid receptor-related orphan receptor (ROR)α/γ. | |||
T12998 | SR10067 | Others , Autophagy | |
SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbα/β(IC50 of 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively),has anxiolytic activity. | |||
T28856 | SSR180711 hydrochloride | SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl | AChR |
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders. | |||
T5163 | SR1001 | ROR | |
SR 1001 is an inverse agonist for RORα/RORγ (Kis: 172/111 nM). | |||
T28855 | SSR126768A | SSR-126768A,SSR 126768A | Oxytocin Receptor |
SSR126768A is a novel and selective, orally active and potent oxytocin (OT) receptor antagonist with inhibitory effects on uterine contractions for the prevention of preterm labor. | |||
T60037 | SR15006 | DNA/RNA Synthesis | |
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM). | |||
T16928 | SR144528 | Cannabinoid Receptor | |
SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM). | |||
T6994 | SR12813 | SR-12813,SR 12813,GW 485801 | HMG-CoA Reductase , Autophagy |
SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist. | |||
T22429 | SR18662 | DNA/RNA Synthesis | |
SR18662, an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM, reduces the viability of multiple colorectal cancer cell lines and induces apoptosis. | |||
T24828 | SR14150 | SR-14150,SR 14150 | |
SR14150 is a partial agonist of high-affinity NOP receptor. | |||
T28846 | SR16835 | AT-202,AT202,SR 16835,SR-16835 | |
SR16835 is a NOP receptor agonist, with low-affinity bifunctional activity at the μ opioid receptor. | |||
T12999 | SR121566A | Others | |
SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa). | |||
T62239 | HSR1304 | ||
HSR1304 (Compound 5d) is a potent inhibitor of NFκB, a multifunctional transcription factor involved in a wide range of human diseases (e.g. cancer, chronic inflammation). HSR1304 has potential for research in cancer dis... | |||
T26223 | SR1555 HCl | SR-1555,SR1555,SR 1555 | |
SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been involved in the pathology of several autoimmune diseases such as rheumatoid arthriti... | |||
T28845 | SR142948A HCl | SR142948A,SR 142948A,SR-142948A,SR142948A hydrochloride | |
SR 142948A is a non-peptide antagonist of neurotensin receptor. SR 142948A affects the expression of c-Fos and has properties of antipsychotic agent. SR 142948A blocks hypothermia and analgesia induced by neurotensin. It... |