Mushroom

Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion

Chitosan (≥98% deacetylated, mushroom) is a biochemical reagent that can be used as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Chitosan (85%-90% deacetylated, mushroom) is a biochemical reagent that functions as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Chitosan (≥95% deacetylated, mushroom) is a biochemical reagent used as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyrosinase effect, with IC50 values of 2.8 mM and 0.6 mM for monophenolase and biphenolase effects, respectively.

Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.

Isoanhydroicaritin is a naturally occurring flavonoid that inhibits physiological melanin synthesis and recovery and inhibits mushroom tyrosinase.

Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, is a candidate as skin-whitening agents.

Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.

4-Isopropylbenzoic acid (Cumic acid) is an aromatic monoterpenoid isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid shows antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive mushroom tyrosinase inhibitor.

Hydrocinnamic alcohol (3-Phenyl-1-Propanol) exists in storax and fern balsam, also present in Vaccinium species fruits, guava fruit and peel, blackberry, other fruits, rum, white wine, shitake mushroom, matsutake mushroom and peated malt. It is a flavoring ingredient.

p-Tolualdehyde is a RIFM flavor that shows inhibition of mushroom tyrosinase.

Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase.

β-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.

Thiambutosine exhibits inhibitory activity against Mycobacterium leprae and mushroom tyrosinase, making it suitable for infection studies.

Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.

Tyrosinase-IN-24 (compound 3b) is an inhibitor of tyrosinase, exhibiting inhibitory activity against mushroom tyrosinase.

Eritadenine (Lentinacin) is a mushroom-derived compound that acts on the adenosine P-site in adipocyte plasma membranes, lowering cholesterol levels and altering phospholipid composition in rat models of hyperhomocysteinemia, used in anxiety disorder studies.

Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.

Fasciculic acid B is the ester of fasciculol B and 3-hydroxy-3-methylglutaric acid. Fasciculic acid B is calmodulin antagonist from mushroom Naematoloma fasciculare.

Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.

MHY908, a novel inhibitor of melanogenesis, potently inhibits mushroom tyrosinase activity in a dose-dependent manner.