Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Adrenergic Receptor
    (19)
  • 5-HT Receptor
    (5)
  • Dopamine Receptor
    (4)
  • Histamine Receptor
    (4)
  • Norepinephrine
    (4)
  • Autophagy
    (1)
  • Endogenous Metabolite
    (1)
  • MMP
    (1)
  • Opioid Receptor
    (1)
  • Others
    (6)
Filter
Search Result
Results for "

α2a adrenergic receptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    30
    TargetMol | Inhibitors_Agonists
  • Natural Products
    1
    TargetMol | Natural_Products
  • Isotope Products
    2
    TargetMol | Isotope_Products
  • Disease Modeling
    1
    TargetMol | Disease_Modeling_Products
Fiduxosin
ABT 980, A 185980.1
T11286208993-54-8In house
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.
  • Inquiry Price
8-10 weeks
Size
QTY
Lusaperidone
R107474
T11894214548-46-6In house
Lusaperidone (R107474) is a potent α2-adrenergic receptor antagonist, a potential radioligand for the α (2)-adrenergic receptor, with inhibitory effects on α2A and α2C, with Ki values of 0.13 and 0.15 nM, respectively.
  • Inquiry Price
6-8 weeks
Size
QTY
Benzquinamide
P2647, BZQ, Benzoquinamide
T1234363-12-7In house
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for α2A, α2B, and α2C adrenergic receptor (α2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively.
  • Inquiry Price
3-6 months
Size
QTY
OPC-28326
T13804167626-17-7In house
OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively.
  • Inquiry Price
8-10weeks
Size
QTY
TargetMol | Inhibitor Sale
Nemazoline Free Base
T71012130759-56-7In house
Nemazoline Free Base acts as an α1-adrenergic agonist and an α2-adrenergic antagonist, and may be used in the treatment of trace amine-associated receptor-related disorders.
  • Inquiry Price
6-8 weeks
Size
QTY
Ziprasidone hydrochloride monohydrate
CP 88059
T0031138982-67-9
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
  • Inquiry Price
Size
QTY
Ziprasidone hydrochloride
Ziprasidone HCl, CP-88059 hydrochloride
T0031L122883-93-6
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
  • Inquiry Price
Size
QTY
Xylometazoline hydrochloride
Xylometazoline HCl
T00421218-35-5
Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Guanfacine hydrochloride
Intuniv hcl, Tenex hcl
T215029110-48-3
Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Guanabenz Acetate
Wy8678 acetate, BR-750, Wytensin
T652223256-50-0
Guanabenz Acetate (Wytensin) is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5, respectively.
  • Inquiry Price
Size
QTY
Norepinephrine
Nor-Epirenan, L-Noradrenaline, Levophed, Levonoradrenaline, Levonor, Arterenol, Aktamin
T704451-41-2
Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumour cells.
  • Inquiry Price
Size
QTY
AGN 192836
T10264171102-29-7In house
AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7 nM, 41 nM, and 6.6 nM for the α2A, α2B, and α2C receptors, respectively.
  • Inquiry Price
8-10 weeks
Size
QTY
Ziprasidone
Geodon, Zeldox, CP-88059
T0031L2146939-27-7
Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
  • Inquiry Price
Size
QTY
Lurasidone hydrochloride
Lurasidone HCl, SM-13496 Hydrochloride
T1735367514-88-3
Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antagonist, an antagonist of the adrenergic α2A and α2C receptors, as well as a partial serotonin 5-HT1A receptor agonist. It is used in the treatment of schizophrenia and bipolar disorder.
  • Inquiry Price
Size
QTY
Brimonidine Tartrate
UK 14304 (tartrate), AGN190342 (tartrate), UK14304 tartrate, AGN190342 tartrate
T642270359-46-5
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension.
  • Inquiry Price
Size
QTY
(S)-Terazosin
T12815109351-33-9
(S)-Terazosin is an active S-enantiomer of Terazosin and acts as a potent, high-affinity antagonist of α-adrenoceptors [α1a, α1b, and α1d-adrenoceptors] with Ki values of 3.91 nM, 0.79 nM, and 1.16 nM, respectively.
  • Inquiry Price
6-8 weeks
Size
QTY
TAAR1 agonist 3
T2000461804129-70-1
TAAR1 agonist 3 is a potent agonist of Trace Amine-Associated Receptor 1 (TAAR1) with a pEC50 value of 7.6. Additionally, it acts as a full agonist at the α2AR with a pEC50 of 6. TAAR1 agonist 3 is utilized in the research of neuropsychiatric disorders.
  • Inquiry Price
10-14 weeks
Size
QTY
TDIQ hydrochloride
T20423415052-05-8
TDIQ hydrochloride is an analog of Amphetamine with high affinity for the α2-adrenergic receptor. This compound acts as a selective ligand for α2-adrenergic receptors, displaying Ki values of 75 nM, 95 nM, and 65 nM for α2A-, α2B-, and α2C-adrenergic receptors, respectively.
  • Inquiry Price
10-14 weeks
Size
QTY
Allyphenyline oxalate
T2043761092984-08-1
The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.
  • Inquiry Price
10-14 weeks
Size
QTY
rs 79948 hydrochloride
T23266186002-54-0
α2-adrenoreceptor antagonist
  • Inquiry Price
6-8 weeks
Size
QTY
rwj 52353
T23281245744-10-9
α2D adrenergic receptor agonist
  • Inquiry Price
6-8 weeks
Size
QTY
AVN-101
T266901061354-48-0
AVN-101 is a highly potent 5-HT7 receptor antagonist with a Ki value of 153 pM. AVN-101 also exhibits considerable affinity for histamine H1 (Ki value of 0.58 nM) and adrenergic α2A, α2B and α2C (Ki values ​​of 0.41-3.6 nM) receptors. AVN-101 has shown good oral bioavailability and brain-blood barrier permeability, low toxicity and reasonable efficacy in animal models of central nervous system diseases.
  • Inquiry Price
Size
QTY
BRL 44408 Maleate Salt
BRL44408 Maleate
T26904681806-46-2
BRL 44408 Maleate is a potent α2A-adrenoceptor antagonist with antidepressant and analgesic activity that reduces lipopolysaccharide (LPS)-induced expression and attenuates endogenous lipopolysaccharide-induced acute lung injury through inhibition of the mitogen-activated protein kinase kinase extracellularly regulated protein kinase signaling pathway in mice.
  • Inquiry Price
6-8 weeks
Size
QTY
Desglymidodrine
ST1059, ST 1059
T31388L3600-87-1
Desglymidodrine (ST 1059) is a selective α1-adrenoceptor agonist and an active metabolite of Midodrine. It is a vasoconstrictor that can be used for cardiovascular research and neurocardiogenic syncope.
  • Inquiry Price
Size
QTY