Senecio

Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury.

Adonifoline is a hepatotoxic pyrrolizidine alkaloid.

Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduc

Cytidine 5'-triphosphate disodium salt is one of the endogenous metabolites and is a cation-permeable ligand-gated ion channel agonist.

Kaempferol 3-O-β-D-galactopyranoside possesses antioxidant, anti-inflammatory, and antinociceptive activities.

Isovanillic acid (3-Hydroxy-4-methoxybenzoic acid) is a natural product isolated from Senecio scandens and exhibits notable anti-inflammatory activities.

Senecionine n-oxide is a major product of pyrrolizidine nucleic alkaloid biosynthesis in unusual root cultures of Trichoderma lucidum.Senecionine N-oxide (Senecionine oxide) has antitumor activity but induces hepatic sinusoidal obstruction syndrome.Senecionine n-oxide acts as a chelating tracer for N-oxide.

Seneciphylline N-oxide is a pyrrolizidine alkaloid obtained from Emilia sonchifolia and is the dehydrogenation product of Senecionine N-oxide.

Platyphylline is a natural product for research related to life sciences. The catalog number is TN4809 and the CAS number is 480-78-4.

D-Otocenine elicites low toxicity, it shows spasmolytic properties .

Florosenine is a natural product of Senecio, Asteraceae. The catalog number is TN4068 and the CAS number is 16958-30-8. Florosenine can be used as a reference standard.

Onetine is a natural product for research related to life sciences. The catalog number is TN4710 and the CAS number is 41451-67-6.

Sarracine N-oxide is a natural product of Senecio, Asteraceae. The catalog number is TN4952 and the CAS number is 19038-27-8. Sarracine N-oxide can be used as a reference standard.

JP-2 is a natural product for research related to life sciences. The catalog number is TN4015 and the CAS number is 60263-06-1.

Macrophylline A shows weak inhibitory action on KCl-induced contraction.

Senecivernine is a natural product of Senecio, Asteraceae. The catalog number is TN4989 and the CAS number is 72755-25-0. Senecivernine can be used as a reference standard.

Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.

Sceleratine is a natural product from Senecio latifolius DC.

Nemorensine is a natural product for research related to life sciences. The catalog number is TN4631 and the CAS number is 50906-96-2.

Sarracine and neosarracine show immunomodulatory activities.

Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer.

1-Decarboxy-3-oxo-ceanothic acid exhibits in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, mediated at least in part by induction of apoptosis. It is cytotoxic against OVCAR-3 and HeLa cancer cell lines with IC50 values of 2.8 and 6.6 microg/mL, respectively, and has an IC50 of 11.3 microg/mL against normal cell line FS-5.

Spartioidine is a natural product of Senecio, Asteraceae. The catalog number is TN5041 and the CAS number is 520-59-2. Spartioidine can be used as a reference standard.

Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.