Araliaceae

Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hematologic cancers, such as leukemia and

Oleanolic acid 28-O-β-D-glucopyranoside (Beta-D-glucopyranosyl oleanolate) is a natural product derived from Hedera nepalensis.

Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.

Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.

Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.

Hederacoside C (Hederasaponin C) is expectorant for Cold and cough relief, Bronchitis.

Coniferin (Abietin) has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin analogue show the exclusive presence of beta-glucosidase activity in the differentiating xylem, similar to peroxidase activity.

Ciwujianoside A1 comes from Acanthopanax senticosus.

Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti

Chikusetsusaponin Ib (Chikusetsu saponin Ib) is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.

Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the m

Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan, has been found to possess obvious pharmacological effects in previous studies.

Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.

Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.

Hederagenin-28-beta-D-glucopyranoside, a triterpenoid saponin isolated from Ilex cornuta, protects against H2O2-induced damage in cardiomyocytes.

Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. It has a role as an antifungal agent and a plant metabolite. It is a member of cinnamaldehydes, a phenylpropanoid and a member of guaiacols. It derives from a cinnamaldehyde.

Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi

Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.

Continentalic acid from Aralia continentalis exhibits minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Methicillin-susceptible Staphylococcus aureus (MSSA), and standard strains.

Hederacoside D is a bioactive saponins from Hedera helix.

Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective activities, inhibits the production of pro-inflammatory cytokines and inhibits the activation of inflammatory signaling pathways, helps neutralize harmful free radicals, protects cells from oxidative damage, and promotes the survival and growth of neurons. And prevent neuronal cell death caused by oxidative stress or neurotoxic compounds, which has the potential to treat neurodegenerative diseases, cardiovascular diseases and liver damage.

Stipuleanoside R2 is a triterpenoid saponin compound from the family Pentacarpaceae that inhibits NF-κB activation and has potential applications in inflammation, immunology, and cancer research.

1. β-Hederin has antileishmanial activity. 2. β-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.

(+)-Isolariciresinol 9'-O-glucoside, a lignan glycoside, can be isolated from various plant species.