Anacardiaceae

Folic acid is an orally active essential nutrient involved in the synthesis of DNA/RNA and the production and maintenance of new cells. It exhibits antidepressant-like effects and can reduce the risk of neural tube defects in newborns. Folate deficiency can cause megaloblastic anemia, macrocytic anemia, neural tube closure defects, tumors, and aging-related diseases. Folic acid is also commonly used in research on folate deficiency-related conditions and to induce acute kidney injury models.

Tannic acid (Gallotannic acid) is a novel hERG channel blocker.

Addition of the Rhamnose (6-Deoxy-L-mannose)-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, inducing fast and transient increases in Ca2 influx and intracellular free Ca2 level.

Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.

Fisetin belongs to a group of natural flavonols with a variety of biological activities, including anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects.

Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.

Choerospondin, a dietary flavonoid glycoside isolated from the bark of the southern date palm (Ziziphus jujuba L.), is a potential α-glucosidase inhibitor with antiproliferative, antioxidant, antitumor, and anti-inflammatory activities that enhances the resistance to oxidative stress, and significantly inhibits inflammatory responses by attenuating mitogen-activated protein kinase phosphorylation and nuclear factor-κ B activation.

3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring formation, and bone resorption in RAW 264.7 cells and bone marrow macrophages induced by NF-κB ligand (RANKL) receptor activators.

Isomangiferin has an antiviral effect, may due to their capability of inhibiting virus replication within cells. It also has antioxidant and radical-scavenging activities.

Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.

Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.

Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical marker of osteoclast function and bone resorption.

3,5-Dihydroxy-4-methoxybenzoic acid is a benzoic acid that can be used in organic synthesis and biological experiments.

Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signa

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells (IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. It inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1, which are known to be activated in colorectal cancer.

(1R)-α-Pinene ((+)-alpha-Pinene) is a volatile substance from plants with antimicrobial activity and anthelmintic activity that reduces the growth of Bacillus cereus populations.

Bicyclo[2.2.1]hept-2-ene is a bridged cycloalkene compound widely used in biochemical experiments and drug synthesis research.

p-Tolyl acetate is an aromatic compound widely used in biochemical experiments and drug synthesis research.

2,6-Di-tert-butyl-4-ethylphenol is a hindered phenol that can be used as an antioxidant to prevent oxidative degradation in plastics, rubber, and oils.

1-Methoxy-4-propylbenzene exhibits antibacterial activity against Mycobacterium tuberculosis and inhibitory activity against PDH, making it suitable for the treatment of tuberculosis infections.

1,2,3,5-Tetramethylbenzene is a poly-methylated benzene widely used in biochemical experiments and drug synthesis research.

Masticadienonic acid is a compound derived from Chios mastic gum, with potential anti-inflammatory and anti-cancer activities. It alleviates colitis in mice by modulating inflammatory responses, gut barrier integrity, and the microbiome. Masticadienonic acid is a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor and can be used for research on diabetes.

Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.

Cardanol triene is a natural phenolic compound that inhibits tyrosinase (IC50 = 40.5 μM) and can be used in related research in the field of life sciences.