viruse

Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).

Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.

Flaviviruses-IN-2 is a potent flaviviruses inhibitor. Flaviviruses-IN-2 reduces West Nile virus (WNV) protease activity and inhibits WNV by 56%.

Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruses, capable of reducing West Nile virus (WNV) protease activity by 54%.

Flaviviruses-Inhibitor-I is several viruses belonging to the family of Flaviviridae inhibitor.

TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses, and inhibits coxsackievirus B3 and poliovirus by interfering with viral RNA synthesis.TTP-8307 can be used in the study of viral infections.

Moroxydine hydrochloride (ABOB hydrochloride) is a synthetic antiviral drug chemically belonging to the series of the heterocyclic biguanidines. It has antiviral activity and is helpful in the prevention and treatment of influenza.

Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.

Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.

(Rac)-X77 (MUN91789) is a potent SARS- CoV- 2 main protease inhibitor.

MBX2329 is a specific inhibitor of HA-mediated viral entry that inhibits H1N1 virus strain high pathogenic avian influenza H5N1 virus strain.

Aristeromycin (U 99468) is a broad-spectrum antiviral antibiotic that targets RNA viruses and is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY).

RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

DSHS00884 is a potent inhibitor of human papillomavirus E6 (IC50: 10 μM).

Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferative effect on tumor cell lines. It i

Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).

LJ-001 shows broad-spectrum activity against virtually all enveloped RNA and DNA viruses. LJ001 inhibits the infection of transmissible gastroenteritis virus (TGEV) and porcine delta coronavirus (PDCoV).

Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.

FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.

Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.

IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.