vesicles — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60043	DPTIP		Phospholipase
	DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.		Phospholipase
T7917	4'-Hydroxychalcone	2-Benzal-4-Hydroxyacetophenone	Proteasome
	4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity		Proteasome
T77579	JC2-11		IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...
T19554	L-Aspartic aicd sodium	L-Aspartic acid sodium,Sodium L-aspartate	Others , Sodium Channel , Endogenous Metabolite
	L-Aspartic aicd sodium (Sodium L-aspartate) is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain membrane vesicles.		Others , Sodium Channel , Endogenous Metabolite
T5850	Benzamil	Benzamil (hydrochloride)	Na+/Ca2+ Exchanger , Sodium Channel
	Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.		Na+/Ca2+ Exchanger , Sodium Channel
T0719	Tetrabenazine	Xenazine,Ro 1-9569	Others , Dopamine Receptor , Monoamine Transporter
	Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high...		Others , Dopamine Receptor , Monoamine Transporter
T6887	MCC950 sodium	CRID3 sodium salt,CP-456773,CP-456773 sodium,MCC950	NOD-like Receptor (NLR) , NOD
	MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs). MCC950 sodium has no effect on other inflammatory vesicles such as AIM2...		NOD-like Receptor (NLR) , NOD
T3534	Tetrabenazine Racemate	Nitoman,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE	Monoamine Transporter
	Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). Tetrabenazine Racemate blocks neurotransmitter uptake into adrenergic storage vesicles and has been ...		Monoamine Transporter
T13133	Tetrabenazine Metabolite	(-)-β-Dihydrotetrabenazine,(-)-β-HTBZ	Monoamine Transporter
	Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetraben...		Monoamine Transporter
TF0112	DPPS	12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na	Others
	DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) is an anionic diacyl-phospholipid, a form of phosphatidylserine (PS), which is a negatively charged phospholipid located in the lobules of cell membranes. DPPS are used t...		Others
T3230	NLRP3-IN-2	5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR) , NOD
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i...		NOD-like Receptor (NLR) , NOD
T2556	Nandrolone decanoate	19-Nortestosterone decanoate	Others , HIV Protease
	Nandrolone decanoate (19-Nortestosterone decanoate) is the decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrolone enter...		Others , HIV Protease
TP1902L1	G-Protein antagonist peptide acetate		Adrenergic Receptor
	G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide acetate inhibits the activation of Gi or Go by M2 muscarinic cho...		Adrenergic Receptor
T0791	Reserpine	Serpalan,Serpasil,Serpivite	Others , Potassium Channel , MRP , Monoamine Transporter , Autophagy
	Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotoni...
T10191L	7-Chlorokynurenic acid	7-chloro-4-hydroxy-2-carboxyquinoline,7-CKA	GluR , NMDAR
	7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake...		GluR , NMDAR
T4969	Guanosine 5'-triphosphate trisodium salt	GTP Trisodium salt,5'-GTP trisodium salt	Endogenous Metabolite
	Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se...		Endogenous Metabolite
T8270	Deserpidine	Harmonyl	RAAS
	Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie...		RAAS
T35606	1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium	1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
	1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. 1,2-Dioleoyl-sn-glycero-3-ph...
T23709	AlphaSYN-IN-NAB2	alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2
	alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ...
T30290	Bam 1745	Bam1745,Pyroglutamyl peptide bam-1745,Bam-1745
	Bam 1745 is a significant adrenomedullary secretory vesicles component.