t 025

T025 is a pan CLK inhibitor with Kds of 4.8, 0.096, 6.5, 0.61, and 0.074 nM for CLK1-4, respectively. T025 displays anti-proliferative activities with IC50s of 30-300 nM in hematological and solid cancer cell lines. T025 can be used in studies about MYC-driven diseases.

Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.

Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.

Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.

Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.

Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.

Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and metabolic in the brain based on the particular disease and clinical condition model. According to the reports, Citric acid trilithium salt tetrahydrate was used as a mood stabilizer when treating bipolar mood disorders (BD) and lower the risk of self-harm in BD patient. In addition,Citric acid trilithium salt tetrahydrate has been the choice drug in the therapy of acute manic episodes.Citric acid trilithium salt tetrahydrate also could dissolve uric acid crystals in urine achieved from patients with gout. Besides,Citric acid trilithium salt tetrahydrate have some dose-dependent side-effects. The the main side-effects of Lithium Citrate is the tendency to inhibit the prostatic acid phosphatase enzyme (PAP), which result in the accumulation of PAP.

Carsalam (2H-1,3-Benzoxazine-2,4(3H)-dione) is a nonsteroidal anti-inflammatory drug.

Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections.

1-Methyl-4-nitro piperazine-d11 is the deuterated version of 1-Methyl-4-nitro piperazine. 1-Methyl-4-nitrosopiperazine (MNP; MeNP; N-Methyl-N'-nitrosopiperazine) is identified as a potential impurity in sartan drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics.

O-Desmethyl pantoprazole o-sulfate-d3 is the deuterium-labeled version of O-Desmethyl pantoprazole o-sulfate.

EOTMBA-d3 is the deuterated form of EOTMBA. EOTMBA serves as a peptide labeling agent suitable for the quantitative analysis of dipeptides and tripeptides.

Acetyl-L-threonine-d3 (N-Acetylthreonine-d3) is the deuterium-labeled form of Acetyl-L-threonine.

Demethyl vandetanib-13C6 is the carbon-13 labeled version of Demethyl vandetanib.

rac-Rotigotine methyl ether amide-d3 is the deuterium-labeled version of rac-Rotigotine methyl ether amide.

N-Nitroso-cilazapril-d2 is the deuterium-labeled form of N-Nitroso-cilazapril.

3-Ethoxyphenol-d5 (Resorcinol monoethyl ether-d5) is a deuterium-labeled version of 3-Ethoxyphenol. The compound, also known as 3-Ethoxyphenol (Resorcinol monoethyl ether), functions as a phosphine ligand and is used to assess the hydrogen bond acceptor capacity of solutes.

Levocloperastine-d4 ((S)-Cloperastine-d4) is the deuterium-labeled version of Levocloperastine.

NNK-13C6 is the compound NNK labeled with carbon-13 (\(^13C\)).

Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. It exhibits anti-hepatitis C virus (HCV) activity in vivo and in vitro, inhibits the replication of MERS and SARS coronaviruses, and promotes antigen-specific CD8(+) T cell activation.