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(3)
By Target- SGK
- CDK(2)
- Casein Kinase(2)
- ROCK(2)
- Aurora Kinase(1)
- Autophagy(1)
- Bcr-Abl(1)
- DNA Alkylation(1)
- IGF-1R(1)
- Others(2)
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Results for "
sgk-1
" in TargetMol Product Catalog- Inhibitors & Agonists7
- PROTAC Products1
URMC-099
T60571229582-33-5
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19 42 14 150 nM, for MLK1 MLK2 MLK3 DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
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CKI-7
CKI 7 2HCl, CKI-7 dihydrochloride, CKI7 2HCl, CKI 7 dihydrochloride, CKI7 dihydrochloride, CKI-7 2HCl
T199131177141-67-1
CKI-7 is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. It also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
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CKI-7 free base
CKI-7
T10829120615-25-0
CKI-7 free base is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor, also inhibiting SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
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SGK1-IN-1
T128901279829-87-6
SGK1-IN-1 is a highly active and selective SGK-1 inhibitor with an IC50 of 1 nM.
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SGK1-IN-2
T128911426214-64-3
SGK1-IN-2 (14h) is a selective inhibitor of serum and glucocorticoid-regulated kinase 1 (SGK1), with an IC50 of 5 nM at a 10 μM ATP concentration.
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PROTAC SGK3 degrader-1
SGK3-PROTAC1
T138472381320-35-8
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, inducing degradation of endogenous SGK3. It inhibits GDC0941-induced proliferation of cancer cells. [5017-88-83-4]
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PIM1-IN-4
T732472762767-48-4
PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1 and also shows significant inhibitory activity against SGK-1, PKA, CaMK-1, GSK3β, and MSK1, making it potentially valuable for cancer research [1].
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