sequencing

DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.

DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly utilized in DNA synthesis and sequencing.

Theaflavin digallate and lactic acid together could reduce herpes simplex virus transmission.

ddATP is a dideoxynucleotide, used as a chain extension inhibitor for DNA polymerase, and used for DNA sequencing by the Sanger method.

(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) is a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).

1, 8-naphthyridine-2,7-diamine can act as a recognition molecule that acts as a universal base pair reader in electronic tunneling for genome sequencing, producing distinguishable features for each DNA base pair under electrical bias.

7-Methylguanine is an orally available PARP1 inhibitor (Ki=61 μM) that competes with the substrate NAD+, exhibiting anticancer activity. As a natural nucleic acid metabolite, it may serve as a probe for protein-DNA interactions.

Antifungalagent 117 is a bipyrrole carboxamide derivative with antifungal activity, exhibiting an EC50 value of 11.58 mg/L against Sclerotinia sclerotiorum. This compound induces cell death by increasing cell membrane permeability, causing an imbalance in osmotic pressure between the interior and exterior of the cell. It also promotes oxidative damage to the cell membrane by inducing the accumulation of reactive oxygen species (ROS), leading to the leakage of cellular contents. RNA sequencing analysis has demonstrated that Antifungalagent 117 disrupts cell membrane structure by downregulating catalase genes and upregulating neutral ceramidase genes, accelerating ceramide metabolism and hastening cell death. The compound holds significant potential for application in plant protection and the control of fungal infections.

ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) tetrasodium is an active metabolite of 2',3'-dideoxyinosine and functions as a chain elongation inhibitor for DNA polymerase. It is utilized in DNA sequencing using the Sanger method and in research related to viral infections.

2'-Deoxytubercidin 5'-triphosphate (C7dATP) sodium is a deoxyadenosine triphosphate (dATP) analog designed to reduce electrophoretic mobility anomalies caused by compression at G or A residues, thereby enhancing the quality of DNA sequencing data.

ddATP (lithium) (2',3'-Dideoxyadenosine 5'-triphosphate (lithium)) is an active metabolite of 2',3'-dideoxyinosine and acts as a chain extension inhibitor of DNA polymerase. It is employed in DNA sequencing using the Sanger method and is also used in studies related to viral infections.

QD325 is a potent redox modulator for the Treatment of Pancreatic Ductal Adenocarcinoma. Nascent RNA sequencing following treatments with QD325 revealed induction of stress responses in the nucleus, endoplasmic reticulum, and mitochondria of pancreatic ca

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)

5-Propargylamino-ddCTP 3TEA is a derivative and modified nucleotide of ddCTP, used in gene sequencing. ddCTP is one of the chain terminators used in Sanger sequencing.

2',3'-Dideoxy-5-iodocytidine, a chemical compound, is employed in gene sequencing and functions as an antibiotic. It exhibits significant efficacy specifically against Mycobacterium.

7-Deaza-7-propargylamino-ddGTP is a gene sequencing analog of dideoxyguanosine triphosphate (ddGTP).

7-Deaza-7-propargylamino-ddGTP 3TEA is a derivative and modified nucleotide of ddGTP, used in gene sequencing. ddGTP is one of the chain terminators used in Sanger sequencing.

7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside compound used in DNA synthesis and sequencing reactions.

7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1) is a nucleotide derivative used in producing thiotriphosphate nucleotide dye terminators for DNA sequencing reactions.

7-Deaza-7-propargylamino-ddATP, an analog of ddATP, serves as a viable option for gene sequencing purposes due to its chemical composition.

7-Deaza-7-propargylamino-ddATP 3TEA is a derivative and modified nucleotide of ddATP, which can be used for gene sequencing. ddATP is one of the chain terminators used in Sanger sequencing.

7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxynucleoside utilized in DNA synthesis and sequencing reactions.

7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, is appropriate for synthesizing thiotriphosphate nucleotide dye terminators used in DNA sequencing reactions.

7-Iodo-7-deaza-2'-deoxyguanosine is a deoxyguanosine derivative used in DNA synthesis and sequencing reactions.