sap 2

SAP2-IN-1 is a secreted aspartate protease 2 (SAP2) inhibitor with potent SAP2 inhibition (IC50: 0.92 μM). It also acts as a virulence factor inhibitor but shows no activity in vitro. SAP2-IN-1 can be utilized for studying infections.

Human β-defensin-2 (HβD-2) is a cationic skin-antimicrobial peptide (SAP) characterized by its small size and rich cysteine content. Produced by various epithelial cells, it exhibits potent antimicrobial properties against gram-negative bacteria and Candida but is not effective against gram-positive Staphylococcus aureus. Given these characteristics, Human β-defensin-2 serves as a valuable tool in colitis research.

Ser-Ala-alloresact, a sperm activating peptide (SAP), plays a pivotal role in the fertilization process through its release from the eggs of marine invertebrates, facilitating sperm activation [1] [2].