psoralen

Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.

Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound found in *Heracleum pyrenaicum* Lam.

Psoralen (Standard) is the standard substance of Psoralen, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a natural product for research related to life sciences. The catalog number is TN3266 and the CAS number is 151121-39-0.

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a natural product for research related to life sciences. The catalog number is TN3267 and the CAS number is 144398-34-5.

8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen is a natural product for research related to life sciences. The catalog number is TN6298 and the CAS number is 889112-17-8.

Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.

Neopsoralen is a furanocoumarin-type psoralen that can be isolated from the plant Heracleum candolleanum (Wight et Arn) Gamble.

5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450) and a metabolite of Xanthotoxin. It is used in the treatment of psoriasis, eczema, vitiligo, and certain cutaneous lymphomas in combination with phototherapy involving exposure to sunlight.

8-Geranyloxypsoralen (Standard) is a reference standard for research and analysis in studies involving 8-Geranyloxypsoralen. 8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.

Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.

8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.

5,8-Dihydroxypsoralen is a natural product from Pueraria lobata (Willd.) Ohwi

8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen is a natural product of Psoralea (Fabaceae) with catalog number TN3281 and CAS number 425680-98-4, used as a reference standard.

Trans-Psoralenoside exhibits hepatoprotective (liver-protective), nephroprotective (kidney-protective), antiulcer, and anticoagulant properties.

Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.

Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.

Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.

Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.

Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

1. Bergaptol (4-Hydroxybergapten) shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.

Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.

1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A^ydiabetic mice.