pregnenolone

Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.

Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid that positively regulates NMDA recordings and is utilized in the study of neuroticism and depression.

Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of neurons from neurotoxic agents.

Pregnenolone Carbonitrile (5-Pregnen-3β-ol-20-one-16α-carbonitrile) is an activator of rodent-PXR and induces the expression of CYP3A.

Allantoin pregnenolone acetate is a biochemical.

Pregnenoloneimpurity 1 is an impurity of Pregnenolone.

Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It can protect the brain from cannabis intoxication

Pregnenolone monosulfate sodium salt is the sodium salt form of Pregnenolone monosulfate.Pregnenolone monosulfate is an endogenous neurosteroid, enhances NMDA receptor-mediated synaptic activity and intracellular Ca²⁺ concentrations, activates CREB phosphorylation, activates TRPM3 channels, and may inhibit GABA A receptors.

Pregnenolone-D4 is a deuterated compound of Pregnenolone. Pregnenolone (T0851) has a CAS number of 145-13-1. Pregnenolone (T0851) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer’s disease.

Sodium Pregnenolone-17α,21,21,21-D4 Sulfate is a deuterated compound of Sodium Pregnenolone Sulfate.

Pregnenolone-d6 (3β-Hydroxy-5-pregnen-20-one-d6) is the deuterated form of Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid and the primary precursor to various steroid hormones, including steroid ketones. It specifically inhibits signaling at the cannabinoid CB1 receptor, counteracting the effects mediated by the CB1 receptor of tetrahydrocannabinol (THC), thereby protecting the brain from cannabis intoxication. Additionally, Pregnenolone serves as an activator of the TRPM3 channel and can weakly activate the TRPM1 channel.

Pregnenolone (Standard) is the standard substance of Pregnenolone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.

Pregnenolone monosulfate sodium (Standard) is a reference standard for research and analysis in studies involving Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium salt is the sodium salt form of Pregnenolone monosulfate.Pregnenolone monosulfate is an endogenous neurosteroid, enhances NMDA receptor-mediated synaptic activity and intracellular Ca²⁺ concentrations, activates CREB phosphorylation, activates TRPM3 channels, and may inhibit GABA A receptors.

Pregnenolone-20,21-13C2, 16,16-D2 In Methanol, Concentration: 100 µg/mL (Standard) is a reference standard of Pregnenolone-[20,21-13C2, 16,16-D2] In Methanol intended for quantitative analysis, quality control, and related biochemical research applications.

Pregnenolone-20,21-13C2, 16,16-D2 Sulfate Sodium Salt (Standard) is a reference standard of Pregnenolone-[20,21-13C2, 16,16-D2] Sulfate Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

Pregnenolone-[20,21-13C2, 16,16-D2] (Standard) is a reference standard of Pregnenolone-[20,21-13C2, 16,16-D2] intended for quantitative analysis, quality control, and related biochemical research applications.

Pregnenolone-D4 (Standard) is a reference standard of Pregnenolone-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Pregnenolone-d4 is a deuterated compound of Pregnenolone. Pregnenolone has a CAS number of 145-13-1. Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer’s disease.

Sodium Pregnenolone-17α,21,21,21-D4 Sulfate (Standard) is a reference standard of Sodium Pregnenolone-17α,21,21,21-D4 Sulfate intended for quantitative analysis, quality control, and related biochemical research applications. Sodium Pregnenolone-17α,21,21,21-d4 Sulfate is a deuterated compound of Sodium Pregnenolone Sulfate.

16,17-Epoxypregnenolone acetate (16alpha,17alpha-Epoxypregnenolone acetate) can be produced by Burkholderia cepacia SE-1.

17a-Hydroxypregnenolone, a pregnane steroid, is a prohormone involved in the synthesis of dehydroepiandrosterone (DHEA).

21-Hydroxypregnenolone is a steroidal natural product and endogenous metabolite, serving as a crucial intermediate in corticosterone synthesis.

17-Hydroxypregnenolone sulfate sodium is a crucial intermediate product in the synthesis of adrenal and gonadal steroids with brain permeability. It acts as a precursor in the biosynthesis of steroid hormones [such as glucocorticoids, sex hormones]. This compound shows potential for use in research related to adrenal function development and neurosteroid-associated diseases [such as cognitive disorders, neurodegenerative diseases].

7α-Hydroxypregnenolone is a bioactive neurosteroid that serves as a key neuronal regulator of movement. By stimulating the dopaminergic system, 7α-Hydroxypregnenolone plays a role in triggering upstream migration in salmon.

16,17-Epoxy-21-acetoxypregnenolone serves as an intermediate in pharmaceutical applications.