phenytoin

Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. It potentially acts by promoting sodium efflux from neurons in the motor cortex, reducing post-tetanic potentiation at synapses. This prevents cortical seizure foci from spreading to adjacent areas and stabilizes the threshold against hyperexcitability. Additionally, it appears to reduce muscle spindle sensitivity to stretch, causing muscle relaxation.

Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .

Phenytoin-D10 is a deuterated isotope-labelled phenytoin for isotope tracing. Phenytoin (T0939)acts as a voltage-gated Na⁺ channel blocker and t-type Ca²⁺ channel inhibitor,exhibiting antiepileptic activity.

Phenytoin (Standard) is the standard substance of Phenytoin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.

Phenytoin sodium (Standard) is a reference standard for research and analysis in studies involving Phenytoin sodium. Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .

Phenytoin-D10 (Standard) is a reference standard of Phenytoin-D10 intended for quantitative analysis, quality control, and related biochemical research applications. Phenytoin-d10 is a deuterated isotope-labelled phenytoin for isotope tracing. Phenytoin acts as a voltage-gated Na⁺ channel blocker and t-type Ca²⁺ channel inhibitor, exhibiting antiepileptic activity.

Fosphenytoin is a phosphate prodrug that can be used as an alternative to intravenous phenytoin for the acute intervention of seizures.Fosphenytoin is hydrolyzed to anticonvulsant phenytoin when administered parenterally.Fosphenytoin can be used in a variety of delivery modes such as intravenous and intraperitoneal.Fosphenytoin can be used in a variety of delivery modes such as intravenous and intraperitoneal.

4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.

(R)-Mephenytoin ((–)-Mephenytoin) is the the R-enantiomer of Mephenytoin which is an anticonvulsant agent.

Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Fosphenytoin-D10 Sodium is a deuterated compound of Fosphenytoin Sodium. Fosphenytoin Sodium (T7066) has a CAS number of 92134-98-0. Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.

(S)-4-Hydroxymephenytoin is a metabolite resulting from the stereoselective metabolism of Mephenytoin. Mephenytoin is an anticonvulsant and serves as a substrate for the enzymes CYP2C19 and CYP2B6.

(S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsant that serves as a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and is used to analyze cytochrome P450 metabolism.

3-Hydroxymephenytoin is a bioactive chemical.

Mephenytoin-D3 is the deuterated form of Mephenytoin (T21425) and can be used for isotope tracing.

4-Hydroxymephenytoin-D3 is the deuterated form of 4-Hydroxymephenytoin (T10147) and can be used for isotope tracing.

Mephenytoin (Standard) is a reference standard for research and analysis in studies involving Mephenytoin. Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.

4-Hydroxymephenytoin (Standard) is a reference standard for research and analysis in studies involving 4-Hydroxymephenytoin. 4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.

Mephenytoin-[13C,D3] (Standard) is a reference standard of Mephenytoin-[13C,D3] intended for quantitative analysis, quality control, and related biochemical research applications.

4-Hydroxymephenytoin-[13C,D3] (Standard) is a reference standard of 4-Hydroxymephenytoin-[13C,D3] intended for quantitative analysis, quality control, and related biochemical research applications.

Denzimol hydrochloride is a new anticonvulsant drug that inhibits electrically and chemically induced tonic seizures but does not stop clonic seizures. It behaves similarly to phenytoin and carbamazepine, but differently from barbiturates and benzodiazepines.

Ethotoin (Peganone), an orally active anticonvulsant agent utilized in epilepsy research, is a hydantoin derivative analogous to phenytoin [1].