mosquito

TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.

VU625 (VU007625) is a selective and potent AeKir1 inhibitor (IC50: 96.8 nM) that acts as a mosquito killer and inhibits AeKir1-mediated currents.

Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.

Benzyl ether (Benzyl oxide) is an organic compound commonly used to protect hydroxyl groups and is mainly used as a toughening agent for nitrocellulose, a solvent for flavors, a rubber antioxidant, and a mosquito repellent. Acetovanillone-Derived benzyl ether has antimicrobial activity.

Tectoquinone exhibits strong mosquito larvicidal activity.

β-Damascone are a series of closely related chemical compounds that are components of a variety of essential oils. The damascones belong to a family of chemicals known as rose ketones, which also includes damascenones and ionones. beta-Damascone is a contributor to the aroma of roses, despite its relatively low concentration, and is an important fragrance chemical used in perfumery.

AChE-IN-73 (compound 6), an insecticide, exhibits potent mosquito inhibitory capabilities, particularly against C. pipiens with an LC 50 of 78.0 mg L. It demonstrates high affinity for acetylcholinesterase (AChE) and nicotinic acetylcholine receptors (nAChR), with respective binding energies of -8.11 kcal mol and -6.27 kcal mol.

AL284 is an effective inhibitor of the Anopheles gambiae acetylcholinesterase 1 (AgAChE1), showing potential for research into mosquito-borne diseases. This compound targets the enzyme that is crucial for the mosquito's neurological processes, providing a foundation for studying diseases transmitted by these insects.

Butyl cinnamate is an agent of mosquito repellent.

N, N-Diethyl-p-toluamide is an agent of mosquito repellent.

Insecticidal agent 20 (Compound 17) is an insecticide that binds to AChBP. It demonstrates effective insecticidal activity against mosquito larvae (LC50: 1.57 ppm) and pupae (LC50: 4.17 ppm).

Niloticin is a mosquito insecticide from Limonia acidissima L.

Etofenprox, a synthetic pyrethroid, has insecticidal efficacy against mosquito larvae & on non-target organisms.

J 2931 is an inhibitor of mosquito larvae growth.

Nepetalactone is found in the plant Nepeta parnassica and has high mosquito repellency properties.

HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 μM) and insulin receptor activity (IC50=14.2 μM and 200 μM, in mosquitoes and mammals, respectively).

Golgicide A-1 (GCA-1) is a moderately potent cis-diastereomer variant of Golgicide A (GCA), designed specifically to inhibit mosquito reproduction.

ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.

Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent.

TCMDC-135051 hydrochloride is a potent, highly selective, low off-target toxicity inhibitor of the protein kinase PfCLK3. TCMDC-135051 hydrochloride blocks the trophozoite to lysosome transition, disrupts transcription and inhibits transmission to mosquito vectors, exhibiting an antiparasitic effect with an EC50 value of 320 nM.

TCMDC-135051 TFA is a potent, highly selective, low off-target toxicity protein kinase PfCLK3 inhibitor that exhibits antiparasitic effects with an EC50 value of 320 nM. TCMDC-135051 TFA blocks the trophozoite to lytic transition, disrupts transcription and inhibits transmission to mosquito vectors.

1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.

DDD01035881 is a novel and highly potent anti-malarial drug that blocks parasite-to-mosquito transmission with nanomolar activity by targeting the Plasmodium vesicle membrane protein Pfs16 and blocking the formation of male gametes in the life cycle of the malaria parasite.

Ethyl 2-ethylhexanoate is a RIFM fragrance and an active ingredient in mosquito repellents.