lilrb-1

LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits considerable diversity in the population, and polymorphisms in the LILRB1 gene have been associated with susceptibility to rheumatoid arthritis and weakly associated with HCMV disease in a subset of patients with HIV. The regulation of phagocytosis by macrophages is an additional key role of LILRB1 signaling. LILRB1 recognizes a wide variety of HLA haplotypes due to its interaction with the invariant β2M subunit of MHC class I, which suggests that this signaling axis is relevant across diverse patient populations.

LILRB1 CD85j ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is F7H3G7.

LILRB1 CD85j ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 75.2 kDa and the accession number is NP_001035762.2.

LILRB1 CD85j ILT2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.08 kDa and the accession number is NP_001035762.2.

LILRB1 CD85j ILT2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.19 kDa and the accession number is XP_045236898.1.

Expression system: HEK293 Cells
Length: 24-458, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 24-458, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 24-458, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 116-461, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 24-221, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 24-458, Partial
Activity: ELISA