krp

KRP-199, a highly potent and selective antagonist for the AMPA receptors, exhibits good neuroprotective effects in vivo.

KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.

KRP-101, a PPARɑ agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.

KRP-109, a neutrophil elastase (NE) inhibitor, acts by decreasing expression of TGF-ß Signal Related Genes.

KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.

KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras. This compound is suitable for use in cancer research [1].

KRpep-2d (TFA) is a potent K-Ras inhibitor that effectively impedes the proliferation of K-Ras-driven cancer cells, making it a valuable asset for cancer research [1].

KRPEP-2D acetate was identified as a K-Ras(G12D) selective inhibitory peptide against the G12D mutant of K-Ras, which is a key member of the Ras protein family and an attractive cancer therapeutic target.

N-5984, a β3-adrenergic receptor agonist, is used potentially for the treatment of obesity, overactive bladder and type 2 diabetes.

Lascufloxacin, a potent and orally active fluoroquinolone antibacterial agent, holds potential for the treatment of various infectious diseases, including lower respiratory tract infections. It effectively inhibits infections caused by a wide range of pathogens, encompassing those resistant to quinolones.

Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Lascufloxacin (KRP-AM-1977) is a potent antibacterial drug candidate. It exhibited the most potent activity against gram-positive bacteria among the quinolones tested. Lascufloxacin showed incomplete cross-resistance against existing quinolone-resistant s

Mocravimod is an agonist of sphingosine 1-phosphate receptor type 1. Mocravimod ameliorates atherosclerosis in LDL-R- - mice. KRP-203 attenuates rat autoimmune myocarditis. KRP-203 combined with cyclosporine prolonged graft survival and abrogated transpla

Neramexane is an NMDA antagonist with neuroprotective effects. Neramexane has antidepressant and nootropic actions. It also acts as a nicotinic acetylcholine receptor antagonist.

Bisegliptin(KRP-104) is a small molecule compound with anti-diabetic activity.

Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.

Imidafenacin hydrochloride is a highly effective and selective M3 receptor inhibitor with a Kb value of 0.317 nM [1].

Imidafenacin-d10 is a deuterated compound of Imidafenacin. Imidafenacin has a CAS number of 170105-16-5. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.