ganoderic

Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum

Ganoderic acid TR is a broad-spectrum inhibitor of influenza neuraminidases (NAs), particularly H1N1 and H5N1 neuraminidases, with IC50 values of 4.6 and 10.9 μM, respectively.

Ganoderic acid M is a useful organic compound for research related to life sciences and the catalog number is T126539.

Ganoderic acid J, a natural terpenoid extracted from Ganoderma lucidum fungus, exhibits anti-inflammatory properties.

Ganoderic acid G is isolated from the surface of Ganoderma lucidum tube layer.

Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg/mL, as demonstrated in its impact on Meth-A tumor cells.

1. Ganoderic acid C6 has antinociceptive activity.

1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.

1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human

Ganoderic acid R, exhibiting notable anticancer properties, effectively hampers tumor growth through apoptosis induction in both multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and sensitive tumor cell line (KB-A-1), demonstrating significant cytotoxicity.

Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].

Ganoderic acid Df, a lanostane-type triterpenoid isolated from the fruiting body of Ganoderma lucidum, potently inhibits aldose reductase with an IC 50 of 22.8 ± 0.6 μM [1].

Ganoderic acid Mk (GA-Mk), a triterpenoid acid derived from Ganoderma lucidum mycelia, exhibits potent anti-proliferative properties and can induce apoptosis in HeLa cells through a mitochondria-mediated pathway, making it significant for cervical cancer research [1] [2].

Ganoderic acid Mf, an antitumor triterpenoid, selectively induces apoptosis in cancer cells through a mitochondria-mediated pathway while demonstrating high selectivity between normal and cancer cells. It also arrests the cell cycle in the G1 phase [1].

Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, diminishes mitochondrial membrane potential and triggers cell apoptosis by activating caspase-9 and caspase-3, thus impairing the antioxidant defense system of cancer cells. Additionally, it elevates intracellular ROS levels, yielding pro-oxidant activities and cytotoxicity [1].

Methyl Ganoderic acid B, a triterpenoid isolated from Ganoderma lucidum, exhibits neuronal survival-promoting effects similar to nerve growth factor (NGF-like) [1].

Ganoderic acid T, a natural compound isolated from Ganoderma lucidum [1], exhibits various pharmacological properties.

Ganoderic acid Me, a triterpenoid present in Ganoderma lucidum [1], exhibits various biological activities.

Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.

A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca

Ganoderic acid A (Standard) is a reference standard for research and analysis in studies involving Ganoderic acid A. 1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation.

Ganoderic acid B (Standard) is a reference standard for research and analysis in studies involving Ganoderic acid B. Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B acts as a telomerase inhibitor to inhibit the activation of Epstein-Barr virus (EBV) antigens. Ganoderic acid B is a moderate inhibitor of HIV-1 protease.

Ganoderic acid D (Standard) is a reference standard for research and analysis in studies involving Ganoderic acid D. 1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.

Ganoderic acid F (Standard) is a reference standard for research and analysis in studies involving Ganoderic acid F. Ganoderic acid F inhibits the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.5+/-0.6 microM.