folate metabolism

Ethopabate (Ethyl pabate) is an inhibitor of folate metabolism, used as a coccidiostat in poultry.

Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.

DHFR-IN-26 is an inhibitor of Escherichia coli dihydrofolate reductase (ecDHFR) with an IC50 value of 0.75 nM. It exhibits broad-spectrum antibacterial activity by interfering with folate metabolism, nucleotide synthesis, and bacterial amino acid metabolic pathways. This compound disrupts bacterial inner membranes, inhibits biofilm formation, and attenuates phage-related processes. DHFR-IN-26 demonstrates low toxicity in non-cancerous cells and is applicable in research involving bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus, multidrug-resistant Escherichia coli, multidrug-resistant Pseudomonas aeruginosa, and lysogenic bacteria.

Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophr

10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate. Folate is a member of the B-vitamin family, which plays a supporting role in a number of key biochemical reactions in the body, including RNA and DNA synthesis. Made up of pteridine, para-aminobenzoic acid, and glutamate, 10-Formyl-5,8-dideazafolic acid is a compound that inhibits de novo folate metabolism. It induces cell cycle arrest at phase G(1)-S, disrupts repair of cells damaged by radiation, and induces apoptosis.

Ethopabate (Standard) is the standard substance of Ethopabate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ethopabate (Ethyl pabate) is an inhibitor of folate metabolism, used as a coccidiostat in poultry.

Tetrahydrofolic acid (Standard) is a reference standard for research and analysis in studies involving Tetrahydrofolic acid. Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that functions as a one-carbon donor in organisms and is involved in growth and metabolism. Tetrahydrofolic acid (Standard) is utilized in biochemical research focused on folate-mediated one-carbon transfer pathways, nucleotide biosynthesis mechanisms, and metabolic flux analysis in cellular proliferation systems.