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Results for "
fk-506
" in TargetMol Product Catalog- Inhibitors & Agonists5
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- Disease Modeling1
Tacrolimus
Fujimycin, FR900506, FK506
T2144104987-11-3
Tacrolimus (FK506, Fujimycin) is a macrolide immunosuppressant that binds to FKBP12 to form a high-affinity complex (Ki = 0.2 nM), which inhibits calcineurin phosphatase activity, thereby suppressing T lymphocyte signal transduction and the transcription and release of IL-2. It exerts potent immunosuppressive effects and can be used to induce immunosuppression models.
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