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Search Result
Results for "
fcγriib
" in TargetMol Product Catalog- Inhibitors & Agonists5
- Inhibitory Antibodies4
- Recombinant Protein2
Omalizumab
T9926242138-07-4
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
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Valziflocept
TAK-752, BAX1810
T808801804910-11-9
Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor designed as a decoy or scavenger to target Fc and FcγR, binding and neutralizing pathogenic IgG. Its utility lies in mitigating autoimmune diseases, with a particular focus on systemic lupus erythematosus (SLE) research [1].
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ADG-106
T9901A-773
ADG-106 is a fully human agonistic monoclonal IgG4 antibody targeting CD137 (4-1BB). It activates CD137 through a potent FcγRIIB-mediated cross-linking mechanism while antagonizing the CD137 ligand. The isotype control for ADG-106 can be referred to as HumanIgG4(S228P) kappa, Isotype Control.
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MGD010
PRV-3279, MGD010
T9901A-816
MGD010 is a bispecific antibody targeting CD32B (FcγRIIb) and CD79B. By simultaneously co-engaging CD32B (FcγRIIb) and the BCR component CD79B, MGD010 delivers an inhibitory signal, thereby suppressing activated B cells. MGD010 shows potential for research in autoimmune diseases.
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