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Search Results for " cysteinyl "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T31162	Cysteinyltyrosine	N-L-Cysteinyl-L-tyrosine,Cys-tyr
	Cysteinyltyrosine is a dipeptide composed of cysteine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T8844	Diflapolin		Others , FLAP , Epoxide Hydrolase
	Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.		Others , FLAP , Epoxide Hydrolase
T1677	Montelukast	Singular	Leukotriene Receptor , Lipoxygenase , LTR
	Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...		Leukotriene Receptor , Lipoxygenase , LTR
T1677L	Montelukast sodium	MK0476	Leukotriene Receptor , LTR
	Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...		Leukotriene Receptor , LTR
T4233L	Cysteinylglycine acetate	Cys-Gly Acetate,Cysteinylglycine acetate（19246-18-5 Free base）	Endogenous Metabolite
	Cysteinylglycine acetate (Cys-Gly Acetate) is an acetate salt of Cysteinylglycine. Cysteinylglycine is an endogenous metabolite. Cysteinylglycine is used in disease diagnosis.		Endogenous Metabolite
T38206	3-Cysteinylacetaminophen (trifluoroacetate salt)	APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)
	3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic...
T31161	Cysteinyllysine
	Cysteinyllysine is a dipeptide composed of cysteine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T31160	Cysteinylcysteine	Cys-cys
	Cysteinylcysteine is a bioactive chemical.
T32099	Homocysteinylpropachlor	Homo-cys-ipa
	Homocysteinylpropachlor is a bioactive chemical.
T15036	Cysteinylglycine TFA		Others
	Cysteinylglycine TFA is an endogenous metabolite. It is used in disease diagnosis.		Others
T19699	Triciribine phosphate	TCN-P,VD 002,VQD-002	Apoptosis , Akt
	Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.		Apoptosis , Akt
T36333	Z-IETD-AFC
	Z-IETD-AFC is a fluorescent substrate for caspase-8 and granzyme B. It can be used to quantify cysteinyl aspartate-8 or granzyme B activity.
T0694	Pranlukast	ONO-1078	Leukotriene Receptor , IL Receptor , Others , TNF , NF-κB , LTR
	Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered aller...
T11388	Gemilukast	ONO-6950	Others
	Gemilukast (ONO-6950) is an orally active and potent dual inhibitor of cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2), inhibits LTC 4-induced bronchoconstriction, and is inhibitory to human CysLT1 and CysLT2...		Others
T68130	Pobilukast	SKF 104353 Z2,SKF 104353	Leukotriene Receptor
	Pobilukast (SKF 104353) is a selective cysteinyl leukotriene receptor antagonist that blocks phosphatidylinositol metabolism and leukotriene D-induced thromboxane synthesis, and can be used to study limiting myocardial d...		Leukotriene Receptor
T28481	Q8 hydrochloride	Q8
	Q8 is an antagonist of cysteinyl leukotreine receptor. Q8 inhibits VEGF-independent angiogenesis.
T27912	LY 290324	LY-290324,LY290324
	LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor.
T37016	Iralukast (CGP 45715A)
	Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
T31080	CP-85958	(+)-Cp 85958,UNII-CU98Q2IL7P
	CP-85958 is a cysteinyl leukotriene antagonist.
T38129	Leukotriene F4	LTF4
	LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contrac...
T15463	(Rac)-HAMI 3379	HAMI 3379	Others
	HAMI 3379 is a potent and selective antagonist of the Cysteinyl leukotriene (CysLT2) receptor. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury. It also attenuates microglia-related inflammat...		Others
T37386	Dihydro Montelukast
	Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing ...
T21864	BAY-u 9773
	BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC 50 for CysLT 1 and CysLT 2. BAY-u9773 is used to the inhibit LT responses [1].
T37492	11-trans Leukotriene C4	11-trans Leukotriene C4
	11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative...
T72145	Montelukast dicyclohexylamine	MK0476 dicyclohexylamine
	Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits a...
TP1816	Urotensin II, mouse
	Jump to search UTS2 Identifiers Aliases UTS2, PRO1068, U-II, UCN2, UII, urotensin 2 External IDs OMIM: 604097 MGI: 1346329 HomoloGene: 4939 GeneCards: UTS2 hide Gene location (Human) Chr. Chromosome 1 (human)[1] Ba...
T37620	Leukotriene C4 methyl ester
	Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular met...
T60439	CAY10789
	CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 μM. CAY10789 is also a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 μM. CAY10789 s...
T83926	S-Geranylgeranyl-L-glutathione	GGG
	S-Geranylgeranyl-L-glutathione acts as a ligand for the orphan G protein-coupled receptor (GPCR) P2RY8, displaying selective affinity by inducing internalization of P2RY8 in preference to the sphingosine-1-phosphate rece...
T37980	N-methyl Leukotriene C4	N-methyl Leukotriene C4
	Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione t...
T38128	Leukotriene D4	Leukotriene D4 MaxSpec® Standard,LTD4
	Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4...

Compounds

Cysteinyltyrosine

T31162

Synonym: N-L-Cysteinyl-L-tyrosine,Cys-tyr

Target: Others, FLAP, Epoxide Hydrolase

Montelukast

T1677

Synonym: Singular

Target: Leukotriene Receptor, Lipoxygenase, LTR

Montelukast sodium

T1677L

Synonym: MK0476

Target: Leukotriene Receptor, LTR

Cysteinylglycine acetate

T4233L

Synonym: Cys-Gly Acetate,Cysteinylglycine acetate（19246-18-5 Free base）

Target: Endogenous Metabolite

3-Cysteinylacetaminophen (trifluoroacetate salt)

T38206

Synonym: APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)

Homocysteinylpropachlor

T32099

Synonym: Homo-cys-ipa

Target:

Cysteinylglycine TFA

T15036

Synonym:

Target: Others

Triciribine phosphate

T19699

Synonym: TCN-P,VD 002,VQD-002

Target: Apoptosis, Akt

Target: Leukotriene Receptor, IL Receptor, Others, TNF, NF-κB, LTR

Synonym: SKF 104353 Z2,SKF 104353

Target: Leukotriene Receptor

Synonym: LY-290324,LY290324

Target:

Iralukast (CGP 45715A)

Synonym: (+)-Cp 85958,UNII-CU98Q2IL7P

11-trans Leukotriene C4

T37492

Synonym: 11-trans Leukotriene C4

Target:

Montelukast dicyclohexylamine

T72145

Synonym: MK0476 dicyclohexylamine

Leukotriene C4 methyl ester

S-Geranylgeranyl-L-glutathione

T83926

Synonym: GGG

Target:

N-methyl Leukotriene C4

T37980

Synonym: N-methyl Leukotriene C4

Target:

Leukotriene D4

T38128

Synonym: Leukotriene D4 MaxSpec® Standard,LTD4

Target:

Cat No.	Product Name	Synonyms	Targets
T1085	L-Glutathione reduced	GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion	Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
	L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo...
T4233	Cysteinylglycine	Cys-Gly	Others , Endogenous Metabolite
	Cysteinylglycine (Cys-Gly), is a biologically important compound since it is formed during the γ-glutamyl cycle. It is a L-cysteinyl peptide, that can be used in the studies of many peptides and important proteins.		Others , Endogenous Metabolite
TN4675	Nortrachelogenin	(-)-Wikstromol,(-)-Nortrachelogenin	Apoptosis , Antifungal
	Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl asparagin-dependent apoptosis.		Apoptosis , Antifungal
TN2554	1-Monopalmitin	Glyceryl palmitate	Apoptosis
	1-Monopalmitin (Glyceryl palmitate) is a small molecule compound extracted from Mougeotia nummuloides and Spirulina major with potential antitumor activity, inhibiting proliferation of A549 and SPC-A1 cells, and inducing...		Apoptosis

Natural Products

L-Glutathione reduced

T1085

Synonym: GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Cysteinylglycine

T4233

Synonym: Cys-Gly

Target: Others, Endogenous Metabolite

Nortrachelogenin

TN4675

Synonym: (-)-Wikstromol,(-)-Nortrachelogenin

Target: Apoptosis, Antifungal

1-Monopalmitin

TN2554

Synonym: Glyceryl palmitate

Target: Apoptosis

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-03749	CYSLTR1 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and...
TMPY-03331	DPEP2 Protein, Human, Recombinant (His)	Human	HEK293
	DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3)...
TMPY-03366	DPEP2 Protein, Human, Recombinant (hFc)	Human	HEK293
	DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3)...
TMPY-01480	LTC4S Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous...
TMPH-03255	PLA2G5 Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), p...
TMPH-02556	PLA2G5 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), p...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatid...