compound 35

mTOR inhibitor 11 is a useful organic compound for research related to life sciences. The catalog number is T9309 and the CAS number is 1195785-35-3.

(E)-3-(p-Tolyl)acrylaldehyde is a cinnamaldehyde and endogenous metabolite commonly used as a food flavoring with inhibitory effect on Coxsackievirus B3 (CC50=3.96 μM), which can be used in biochemical experiments and organic synthesis.

Bonaniol A is a useful organic compound for research related to life sciences. The catalog number is T123836 and the CAS number is 96917-35-0.

Saccatoside is a useful organic compound for research related to life sciences. The catalog number is T124080 and the CAS number is 85819-35-8.

Ferkuhinin is a useful organic compound for research related to life sciences. The catalog number is T124887 and the CAS number is 408311-35-3.

Antibiotic LL-D253gamma is a useful organic compound for research related to life sciences. The catalog number is T125005 and the CAS number is 34288-35-2.

Populoside is a useful organic compound for research related to life sciences. The catalog number is T125159 and the CAS number is 26632-35-9.

Parthenocissin A is a useful organic compound for research related to life sciences. The catalog number is T125351 and the CAS number is 212513-35-4.

Antibiotic Sch 60057 is a useful organic compound for research related to life sciences. The catalog number is T125403 and the CAS number is 203061-35-2.

Caffeic acid 4-O-glucoside (Linocaffein), a glycosylation product of Caffeic acid, reverses Aβ25-35-induced axonal atrophy and induces axonal regeneration in mouse cortical neurons, and can be used in Alzheimer's disease research.

Ganoderitriol M is a useful organic compound for research related to life sciences. The catalog number is T126126 and the CAS number is 1265906-35-1.

Ciwujianoside D1 is a useful organic compound for research related to life sciences. The catalog number is T126335 and the CAS number is 114912-35-5.

Angoroside A is a useful organic compound for research related to life sciences. The catalog number is T126389 and the CAS number is 111316-35-9.

Amburoside A is a useful organic compound for research related to life sciences. The catalog number is T126395 and the CAS number is 110978-35-3.

3-O-Caffeoyl-4-O-sinapoylquinic acid is a useful organic compound for research related to life sciences. The catalog number is T126405 and the CAS number is 110241-35-5.

Fellutanine A is a useful organic compound for research related to life sciences. The catalog number is T129801 and the CAS number is 175414-35-4.

Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.

URAT1&XO Inhibitor 3 (compound 27) is an orally effective anti-gout agent targeting XO (IC50: 35 nM) and URAT1 (IC50: 31 nM). This compound exhibits favorable pharmacological and pharmacokinetic (PK) characteristics, as well as in vivo safety.

STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.

KRAS inhibitor-35 (compound 72) is a KRAS inhibitor with an IC50 of 2 nM, utilized in tumor research.

HDAC6-IN-50 (Compound 4) is an effective inhibitor of HDAC6 with an IC50 value of 35 nM. It is utilized in the study of Parkinson's disease (PD) and Alzheimer's disease (AD).

LSD1-IN-35 (Compound Z-1) is a selective inhibitor of LSD1, exhibiting an IC50 of 108 nM. This compound inhibits the demethylation of H3K4me1 2 and acts as an immunomodulator. Additionally, LSD1-IN-35 enhances the responsiveness of gastric cancer cells to T-cell killing by reducing PD-L1 expression, thereby weakening the PD-1 PD-L1 interaction.

BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).

CDK9-IN-35 (compound 10j) acts as an inhibitor of CDK9 CyclinT1, exhibiting an IC50 of 10.2 nM. It also shows an IC50 of 20 nM against the HCT-116 cell line.