ccdc

TGR5 is a potent TGR5(GPCR19) agonist.

Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centromeric protein CCDC61, designed for the specific isolation of intact centromeres.

Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotin-modified peptide derived from the centromeric protein CCDC61, capable of specifically isolating intact centromeres.

Unesbulin (PTC596) is an orally active, selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).

PROTACCdc25 degrader-1 (Compound D3) is an effective Cdc25 PROTAC degrader, with DC50 values of 0.97, 2.02, and 4.67 μM for Cdc25A, Cdc25B, and Cdc25C, respectively. It induces cell cycle arrest and apoptosis in cancer cells while inhibiting cell migration.

RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.

Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion).