cardiotonic

Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.

Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.

D-Glucose (Glucopyranose) is a monosaccharide, a natural glucose, a sweetener. D-Glucose is the main functional substance of living organisms, and is used as a nutrient in medicine, with diuretic, detoxification and cardiotonic effects.

6-(γ,γ-Dimethylallylamino)purine (Triacanthine), which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic.

OPC 8490 free base is a novel positive inotropic vasodilator and a cardiotonic agent that increases Ca currents in a dose-dependent and reversible manner and can be used to study cardiovascular diseases.

Milrinone Lactate is a positive inotropic cardiotonic compound. Milrinone Lactate has vasodilator properties, inhibiting cAMP phosphodiesterase type 3 activity in the myocardium and vascular smooth muscle.

Prinoxodan is a potent phosphodiesterase 3 (PDE3) inhibitor. It exerts cardiotonic and vasodilatory effects by increasing intracellular cAMP levels, used for heart failure and cardiovascular research.

Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure.

SCH00013 is an agent of cardiotonic that primarily acts via an increase in myofibrillar Ca++ sensitivity. SCH00013 have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.

Bufalin is a natural product and a Na⁺/K⁺-ATPase inhibitor (IC50 ≈ 40–45 nM) with favorable cell permeability. By binding to α subunits such as ATP1A1, bufalin induces calcium overload and pyroptosis, and can be used for experimental research and therapeutic exploration in various cancers.

Tazolol is a selective beta1-agonist, a coronary treatment agent, and a cardiotonic.

Lixazinone sulfate is a cyclic adenosine monophosphate phosphodiesterase (cAMP PDE) inhibitor with cardiotonic properties.

Anhydro-Ouabain (compound 20) is a cardiotonic steroid with anti-inflammatory and neuroprotective properties, making it useful for neurological research.

Octopamine, an alpha-adrenergic sympathomimetic amine biosynthesized from tyramine, is used to treat hypotension and may act as a cardiotonic. It may be found in the platelets, CNS, and invertebrate nervous systems.

ASI-222 is an aminoglycoside cardiotonic compound. It functions by inhibiting sodium-potassium ATPase (Na+/K+ ATPase) and exhibits positive inotropic effects. ASI-222 can be utilized in cardiovascular disease research.

Acrihellin is a cardioactive steroid, a cardiotonic drug.

AR-L 57 CL is a cardiotonic agent.

Bemarinone is a clinical cardiotonic agent.

Dobutamine lactobionate is a cardiotonic.

Isomazole hydrochloride is a cardiotonic.

Levdobutamine lactobionate is a cardiotonic.

OPC 8490 HCl is a cardiotonic agent and a positive inotropic vasodilator that increases Ca current (ICa) in a dose-dependent and reversible manner and prolongs atrial action potential in a concentration-dependent manner.

RS 1893 is an orally active cardiotonic agent and its structure is different from that of cardiac glycosides and beta-stimulants.